Determining the distribution of disease prevalence among heterogeneous populations at the
national scale is fundamental for epidemiology and public health. Here, we use a …

Introduction: Fetal hemoglobin is an important factor in modulating the severity of sickle cell
anemia. Its level in peripheral blood underlies strong genetic determination. Associated loci …

abstract We identified mitochondrial DNA haplogroups A, B, C, and D in 75 present-day
Maya individuals, 24 Maya individuals of the colonial period, and 1 pre-Columbian Maya …

Migration to urban centres is among the most important forces in contemporary urban
studies. In this paper, we study how the demography and epidemic profile of a community …

Background Colombia has a mestizo population and the prevalence of haemoglobin
variants varies according to each region, but heterozygous carriers can be found in all of …

The objective of this study was identify the frequency of Beta globin cluster's haplotypes
present in sickle cell anemia patients in Colombia, to establish the presence of non-African …

Background. Malaria is an endemic disease present in many areas of Colombia. In the city
of Buenaventura (Colombian Pacific), there is a high incidence of malaria cases, with a high …

Malari a is an endemic disease in a large part of Colombia, and the city of Buenaventura
reports one of the highest malaria infection rates. Some genetic variants confer resistance to …

In regions with an Afro-descendant population and where malaria is endemic, high
frequencies of polymorphisms have been found that confer resistance to this disease, such …

Objetives To estimate the frequency distribution, both allelic and genotypic, of the APOE
gene in the Afro-descendant population of Buenaventura, Colombia. Methods Three …