Lipid raft facilitated receptor organization and signaling: a functional rheostat in embryonic development, stem cell biology and cancer

A Roy, SK Patra - Stem cell reviews and reports, 2023 - Springer
Molecular views of plasma membrane organization and dynamics are gradually changing
over the past fifty years. Dynamics of plasma membrane instigate several signaling nexuses …

An overview of 5-HT3 receptor antagonists as a treatment option for irritable bowel syndrome with diarrhea

K Merecz, M Hirsa, O Biniszewska… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder
characterized by abdominal pain, discomfort, and altered bowel habits, which affects the …

[PDF][PDF] 5-羟色胺与腹泻型肠易激综合征相关性及中医药调控研究进展

苏海霞, 付兆媛, 高永泽, 尉戎戎, 钟建春 - 中国全科医学, 2023 - docs.cn-healthcare.com
5-羟色胺是影响腹泻型肠易激综合征患者胃肠道功能活动的重要脑肠肽. 近年来研究发现5-
羟色胺的合成, 释放, 与受体结合及重摄取等信号传导过程中, 任一环节发生异常均有可能导致 …

5-HT3 Receptors on Mitochondria Influence Mitochondrial Function

STRB Rao, I Turek, J Ratcliffe, S Beckham… - International Journal of …, 2023 - mdpi.com
The 5-hydroxytryptamine 3 (5-HT3) receptor belongs to the pentameric ligand-gated cation
channel superfamily. Humans have five different 5-HT3 receptor subunits: A to E. The 5-HT3 …

Phylogenetic analyses of 5-hydroxytryptamine 3 (5-HT3) receptors in Metazoa

STRB Rao, I Turek, HR Irving - Plos one, 2023 - journals.plos.org
The 5-hydroxytrptamine 3 (5-HT3) receptor is a member of the'Cys-loop'family and the only
pentameric ligand gated ion channel among the serotonin receptors. 5-HT3 receptors play …

TREM-1 inhibition or ondansetron administration ameliorates NLRP3 inflammasome and pyroptosis in traumatic brain injury-induced acute lung injury

F Li, N Qin, Y Yu, R Dong, X Li, S Gong… - Archives of Medical …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction Recently, NLR family pyrin domain containing 3 (NLRP3) and pyroptosis have
been reported to be involved in traumatic brain injury-induced acute lung injury (TBI-ALI) …

Shaoyao Decoction reduced T lymphocyte activation by regulating of intestinal flora and 5-hydroxytryptamine metabolism in ulcerative colitis

J Zhen, Y Li, Y Zhang, Y Zhou, L Zhao, G Huang, A Xu - Chinese Medicine, 2024 - Springer
Abstract Background Shaoyao Decoction (SYD) is a widely recognized herbal formula
utilized in traditional Chinese medicine for the treatment of diarrhea. Although it has …

Role of Serotonergic System in Regulating Brain Tumor-Associated Neuroinflammatory Responses

S Karmakar, G Lal - Neuroprotection: Method and Protocols, 2024 - Springer
Serotonin signaling regulates wide arrays of both neural and extra-neural functions.
Serotonin is also found to affect cancer progression directly as well as indirectly by …

N-(3-((3-(trifluoromethyl) phenyl) selanyl) prop-2-yn-1-yl) benzamide induces antidepressant-like effect in mice: involvement of the serotonergic system

CS Pires, MJ da Rocha, MH Presa, NP Zuge… - …, 2024 - Springer
Objective To evaluate the antidepressant-like effect of N-(3-((3-(trifluoromethyl) phenyl)
selenyl) prop-2-yn-1-yl) benzamide (CF 3 SePB) in mice and the involvement of the …

Role of 5-hydroxytryptamine type 3 receptors in the regulation of anxiety reactions

Y Du, Z Li, Y Zhao, J Han, W Hu, Z Liu - Journal of Zhejiang University …, 2024 - Springer
Hydroxytryptamine (5-HT) type 3 receptor (5-HT3R) is the only type of ligand-gated ion
channel in the 5-HT receptor family. Through the high permeability of Na+, K+, and Ca2+ …