Metabolic adaptations in prostate cancer

M Pujana-Vaquerizo, L Bozal-Basterra… - British Journal of …, 2024 - nature.com
Prostate cancer is one of the most commonly diagnosed cancers in men and is a major
cause of cancer-related deaths worldwide. Among the molecular processes that contribute …

Metabolic heterogeneity in cancer

M Demicco, XZ Liu, K Leithner, SM Fendt - Nature Metabolism, 2024 - nature.com
Cancer cells rewire their metabolism to survive during cancer progression. In this context,
tumour metabolic heterogeneity arises and develops in response to diverse environmental …

Effects of dietary intervention on human diseases: molecular mechanisms and therapeutic potential

YL Xiao, Y Gong, YJ Qi, ZM Shao… - Signal Transduction and …, 2024 - nature.com
Diet, serving as a vital source of nutrients, exerts a profound influence on human health and
disease progression. Recently, dietary interventions have emerged as promising adjunctive …

Metabolic landscape of disseminated cancer dormancy

S Drapela, BM Garcia, AP Gomes, AL Correia - Trends in Cancer, 2024 - cell.com
Cancer dormancy is a phenomenon defined by the entry of cancer cells into a reversible
quiescent, nonproliferative state, and represents an essential part of the metastatic cascade …

Diagnosis and prognosis prediction of gastric cancer by high-performance serum lipidome fingerprints

ZR Cai, W Wang, D Chen, HJ Chen, Y Hu… - EMBO Molecular …, 2024 - embopress.org
Early detection is warranted to improve prognosis of gastric cancer (GC) but remains
challenging. Liquid biopsy combined with machine learning will provide new insights into …

Emerging targets in lipid metabolism for cancer therapy

AR Terry, N Hay - Trends in Pharmacological Sciences, 2024 - cell.com
Cancer cells perturb lipid metabolic pathways for a variety of pro-tumorigenic functions, and
deregulated cellular metabolism is a hallmark of cancer cells. Although alterations in lipid …

Metabolic Signaling in Cancer Metastasis

S Krieg, SI Fernandes, C Kolliopoulos, M Liu, SM Fendt - Cancer Discovery, 2024 - AACR
Metastases, which are the leading cause of death in patients with cancer, have metabolic
vulnerabilities. Alterations in metabolism fuel the energy and biosynthetic needs of …

[HTML][HTML] Theoretical Framework and Emerging Challenges of Lipid Metabolism in Cancer

Q Gu, Y Wang, P Yi, C Cheng - Seminars in Cancer Biology, 2024 - Elsevier
Elevated lipid metabolism is one of hallmarks of malignant tumors. Lipids not only serve as
essential structural components of biological membranes but also provide energy and …

Integrated multi‐omics profiling landscape of organising pneumonia

Y Tang, C Chu, S Bu, Q Sun, A Liu, J Xie… - Clinical and …, 2024 - Wiley Online Library
Background Organising pneumonia (OP) is one of the most common and lethal diseases in
the category of interstitial pneumonia, along with lung cancer. Reprogramming of lipid …

Adapt and shape: metabolic features within the metastatic niche

E Pranzini, L Ippolito, E Pardella, E Giannoni… - Trends in Endocrinology …, 2024 - cell.com
The success of disseminating cancer cells (DTCs) at specific metastatic sites is influenced
by several metabolic factors. Even before DTCs arrival, metabolic conditioning from the …