Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements
V Aggarwal, HS Tuli, F Thakral… - Experimental …, 2020 - journals.sagepub.com
Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-
spectrum applicability to prevent dreadful diseases such as cardiovascular disease …
spectrum applicability to prevent dreadful diseases such as cardiovascular disease …
The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline
J Melrose - Antioxidants, 2023 - mdpi.com
Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …
Neuromodulatory effects of hesperidin against sodium fluoride-induced neurotoxicity in rats: Involvement of neuroinflammation, endoplasmic reticulum stress …
Fluoride is an element with toxic properties and has been proven to have some adverse
effects on many soft tissues, including brain tissue. This study aims to evaluate the protective …
effects on many soft tissues, including brain tissue. This study aims to evaluate the protective …
Progress of research on the role of active ingredients of Citri Reticulatae Pericarpium in liver injury
S Gao, X Chen, Z Yu, R Du, B Chen, Y Wang, X Cai… - Phytomedicine, 2023 - Elsevier
Background Liver is a vital organ responsible for metabolizing and detoxifying both
endogenous and exogenous substances in the body. However, it is susceptible to damage …
endogenous and exogenous substances in the body. However, it is susceptible to damage …
Hesperetin as an anti-SARS-CoV-2 agent can inhibit COVID-19-associated cancer progression by suppressing intracellular signaling pathways
H Zalpoor, M Bakhtiyari, H Shapourian… - …, 2022 - Springer
Hesperetin, an aglycone metabolite of hesperidin with high bioavailability, recently gained
attention due to its anti-COVID-19 and anti-cancer properties. Multiple studies revealed that …
attention due to its anti-COVID-19 and anti-cancer properties. Multiple studies revealed that …
Attenuation of sodium arsenite-induced cardiotoxicity and neurotoxicity with the antioxidant, anti-inflammatory, and antiapoptotic effects of hesperidin
In the scope of the study, the protective effect of hesperidin (HES), a flavanone glycoside,
was investigated against sodium arsenite (NaAsO 2, SA) induced heart and brain toxicity …
was investigated against sodium arsenite (NaAsO 2, SA) induced heart and brain toxicity …
The effects of hesperidin supplementation on cardiovascular risk factors in adults: a systematic review and dose–response meta-analysis
Hesperidin is a naturally occurring bioactive compound that may have an impact on
cardiovascular disease risks, but the evidence is not conclusive. To investigate further, this …
cardiovascular disease risks, but the evidence is not conclusive. To investigate further, this …
A review of plant extracts and plant-derived natural compounds in the prevention/treatment of neonatal hypoxic-ischemic brain injury
H Mohsenpour, M Pesce, A Patruno, A Bahrami… - International journal of …, 2021 - mdpi.com
Neonatal hypoxic-ischemic (HI) brain injury is one of the major drawbacks of mortality and
causes significant short/long-term neurological dysfunction in newborn infants worldwide. To …
causes significant short/long-term neurological dysfunction in newborn infants worldwide. To …
The effect of hesperidin supplementation on metabolic profiles in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial
Purpose Hesperidin as an antioxidant flavonoid exerts anti-adipogenic, anti-inflammatory,
anti-oxidant and anti-hypercholesterolemic effects. Besides, the increasing prevalence of …
anti-oxidant and anti-hypercholesterolemic effects. Besides, the increasing prevalence of …
Taurine and hesperidin rescues carbon tetrachloride-triggered testicular and kidney damage in rats via modulating oxidative stress and inflammation
YM Abd-Elhakim, MH Ghoneim, LLM Ebraheim… - Life Sciences, 2020 - Elsevier
Aims: This study assessed the prophylactic or therapeutic effects of taurine (TR) and/or
hesperidin (HES) on carbon tetrachloride (CCl 4) induced acute kidney and testicular injury …
hesperidin (HES) on carbon tetrachloride (CCl 4) induced acute kidney and testicular injury …