Sources, formulations, advanced delivery and health benefits of probiotics

U Roobab, Z Batool, MF Manzoor, MA Shabbir… - Current Opinion in Food …, 2020 - Elsevier
Highlights•Different studies related to improve probiotic formulations are
described.•Potential sources of probiotics have been discussed to help researchers.•Health …

Microbial-based and microbial-targeted therapies for inflammatory bowel diseases

A Oka, RB Sartor - Digestive diseases and sciences, 2020 - Springer
Inflammatory bowel diseases (IBD), including Crohn's disease, ulcerative colitis, and
pouchitis, are chronic, relapsing intestinal inflammatory disorders mediated by dysregulated …

Choosing an appropriate probiotic product for your patient: An evidence-based practical guide

JC Sniffen, LV McFarland, CT Evans, EJC Goldstein - PloS one, 2018 - journals.plos.org
Introduction Clinicians and patients face a daunting task when choosing the most
appropriate probiotic for their specific needs. Available preparations encompass a diverse …

Local delivery of macromolecules to treat diseases associated with the colon

A Bak, M Ashford, DJ Brayden - Advanced drug delivery reviews, 2018 - Elsevier
Current treatments for intestinal diseases including inflammatory bowel diseases, irritable
bowel syndrome, and colonic bacterial infections are typically small molecule oral dosage …

Contribution of Lactobacilli on Intestinal Mucosal Barrier and Diseases: Perspectives and Challenges of Lactobacillus casei

D Qin, Y Ma, Y Wang, X Hou, L Yu - Life, 2022 - mdpi.com
The intestine barrier, the front line of normal body defense, relies on its structural integrity,
microbial composition and barrier immunity. The intestinal mucosal surface is continuously …

Potential roles for probiotics in the treatment of COVID-19 patients and prevention of complications associated with increased antibiotic use

R Kullar, S Johnson, LV McFarland, EJC Goldstein - Antibiotics, 2021 - mdpi.com
Medical care for patients hospitalized with COVID-19 is an evolving process. Most COVID-
19 inpatients (58–95%) received empiric antibiotics to prevent the increased mortality due to …

Lactobacillus paracasei K5 displays adhesion, anti-proliferative activity and apoptotic effects in human colon cancer cells

P Chondrou, A Karapetsas, DE Kiousi… - Beneficial …, 2018 - wageningenacademic.com
Lactobacillus paracasei K5 is a lactic acid bacteria (LAB) strain, isolated recently from feta-
type cheese. Its probiotic potential has been demonstrated in a series of established in vitro …

Potential role of probiotics in reducing Clostridioides difficile virulence: Interference with quorum sensing systems

S Gunaratnam, M Millette, LV McFarland… - Microbial …, 2021 - Elsevier
Opportunistic pathogenic bacteria may cause disease after the normally protective
microbiome is disrupted (typically by antibiotic exposure). Clostridioides difficile is one such …

Lactobacillus acidophilus LA-5 Ameliorates Inflammation and Alveolar Bone Loss Promoted by A. actinomycetemcomitans and S. gordonii in Mice and Impacts Oral …

MR Bueno, FH Martins, CM Rocha, D Kawamoto… - Microorganisms, 2024 - mdpi.com
The benefits of probiotics on dysbiotic microbiomes and inflammation are dependent on the
tested strain, host factors, and the resident microbiome. There is limited knowledge on the …

Antibacterial Activity of Bifidobacterium breve Against Clostridioides difficile

J Yang, H Yang - Frontiers in cellular and infection microbiology, 2019 - frontiersin.org
Bifidobacterium breve (YH68) is widely used in the fields of food fermentation and
biomedicine. In this study, we explored the antibacterial activity of the cell free culture …