Adolescence represents a critical period for brain and behavioural health and characterised
by the onset of mood, psychotic and anxiety disorders. In rodents, neurogenesis is very …

Chronic stress-induced emotional disorders like anxiety and depression involve imbalances
between the excitatory glutamatergic system and the inhibitory GABAergic system in the …

Immediate-early genes (IEGs) are rapidly activated after sensory and behavioral experience
and are believed to be crucial for converting experience into long-term memory. Neuronal …

Adolescence is a window of vulnerability to environmental factors such as chronic stress that
can disrupt brain development and cause long-lasting behavioral dysfunction, as seen in …

Stress-induced modifications of the prefrontal cortex (PFC) are believed to contribute to the
onset of mood disorders, such as depression and anxiety, which are more prevalent in …

The prefrontal cortex (PFC) is highly sensitive to the effects of stress, a known risk factor of
mood disorders including anxiety and depression. Abnormalities in PFC functioning have …

Classical studies have shown that neuronal immediate-early genes (IEGs) play important
roles in synaptic processes critical for key brain functions. IEGs are transiently activated and …

There is an urgent need to develop more effective treatments for stress-related illnesses,
which include depression, post-traumatic stress disorder, and anxiety. We view animal …

Social withdrawal is found across neuropsychiatric disorders and in numerous animal
species under various conditions. It has substantial impact on the quality of life in patients …

Abstract ALBRECHT, A., MÜLLER, I., ARDI, Z., ÇALIŞKAN, G., GRUBER, D., IVENS, S.,
SEGAL, M., BEHR, J., HEINEMANN, U., STORK, O., and RICHTER-LEVIN, G …