Abstract Peroxiredoxins (Prx), thiol-dependent peroxidases, were first identified as H 2 O 2
detoxifiers, and more recently as H 2 O 2 sensors, intermediates in redox-signaling …

Fluorescence lifetime imaging microscopy (FLIM) is a reliable method that achieves imaging
by detecting fluorescence lifetimes within samples. Owing to its unique temporal …

Peroxiredoxins play central roles in the detoxification of reactive oxygen species and have
been modelled across multiple organisms using a variety of kinetic methods. However, the …

We have studied the reduction reactions of two cytosolic human peroxiredoxins (Prx) in their
disulfide form by three thioredoxins (Trx; two human and one bacterial), with the aim of better …

Thioredoxin, glutaredoxin and peroxiredoxin systems play central roles in redox regulation,
signaling and metabolism in cells. In these systems, reducing equivalents from NAD (P) H …

Human peroxiredoxin 1 and peroxiredoxin 2 (HsPrx1 and HsPrx2), both cytosolic
antioxidant enzymes share more than 90% sequence similitude, peroxide substrate …

Peroxiredoxins (Prx) are ubiquitous, highly conserved peroxidases whose activity depends
on catalytic cysteine residues. The Prx1-class of the peroxiredoxin family, also called typical …

Hydrogen peroxide is a cellular oxidant that disrupts numerous cellular systems by being
readily converted to the hydroxyl radical, which indiscriminately reacts with biomolecules …

Abstract Peroxiredoxin 1 (Prdx1) is a ubiquitous peroxide scavenging enzyme with
secondary signalling and chaperone functions. Like many other peroxiredoxins, Prdx1 exists …

Las peroxiredoxinas (Prx) son peroxidasas que catalizan la reducción de peróxido de
hidrógeno (H2O2) por reductores endógenos usando uno o dos residuos de cisteína. En …