Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W Xiao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Hydrogen cyanide production by soil bacteria: Biological control of pests and promotion of plant growth in sustainable agriculture

A Sehrawat, SS Sindhu, BR Glick - Pedosphere, 2022 - Elsevier
Currently, plant diseases and insect infestations are mainly controlled by the extraneous
application of pesticides. Unfortunately, the indiscriminate use of such agrochemicals can …

Regulation of Biofilm Exopolysaccharide Biosynthesis and Degradation in Pseudomonas aeruginosa

LZ Ma, D Wang, Y Liu, Z Zhang… - Annual review of …, 2022 - annualreviews.org
Microbial communities enmeshed in a matrix of macromolecules, termed as biofilms, are the
natural setting of bacteria. Exopolysaccharide is a critical matrix component of biofilms …

A Pseudomonas aeruginosa small RNA regulates chronic and acute infection

P Cao, D Fleming, DA Moustafa, SK Dolan… - Nature, 2023 - nature.com
The ability to switch between different lifestyles allows bacterial pathogens to thrive in
diverse ecological niches,. However, a molecular understanding of their lifestyle changes …

The Formation of Biofilms by Pseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms

T Rasamiravaka, Q Labtani, P Duez… - BioMed research …, 2015 - Wiley Online Library
P. aeruginosa is an opportunistic pathogenic bacterium responsible for both acute and
chronic infections. Beyond its natural resistance to many drugs, its ability to form biofilm, a …

Biofilm, pathogenesis and prevention—a journey to break the wall: a review

P Gupta, S Sarkar, B Das, S Bhattacharjee… - Archives of …, 2016 - Springer
Biofilms contain group (s) of microorganisms that are found to be associated with the biotic
and abiotic surfaces. Biofilms contain either homogenous or heterogeneous populations of …

Biofilm Matrix and Its Regulation in Pseudomonas aeruginosa

Q Wei, LZ Ma - International journal of molecular sciences, 2013 - mdpi.com
Biofilms are communities of microorganisms embedded in extracellular polymeric
substances (EPS) matrix. Bacteria in biofilms demonstrate distinct features from their free …

A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria

RD Hood, P Singh, FS Hsu, T Güvener, MA Carl… - Cell host & …, 2010 - cell.com
The functional spectrum of a secretion system is defined by its substrates. Here we analyzed
the secretomes of Pseudomonas aeruginosa mutants altered in regulation of the Hcp …

Regulation of bacterial virulence by Csr (Rsm) systems

CA Vakulskas, AH Potts, P Babitzke… - Microbiology and …, 2015 - Am Soc Microbiol
Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …