Prostaglandin E2 and cancer: insight into tumor progression and immunity

F Finetti, C Travelli, J Ercoli, G Colombo, E Buoso… - Biology, 2020 - mdpi.com
Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …

Exosome-based nanoimmunotherapy targeting TAMs, a promising strategy for glioma

H Luo, H Zhang, J Mao, H Cao, Y Tao, G Zhao… - Cell Death & …, 2023 - nature.com
Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …

[HTML][HTML] TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling

P Peng, H Zhu, D Liu, Z Chen, X Zhang, Z Guo… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: In the glioblastoma (GBM) microenvironment, tumor-associated macrophages
(TAMs) are prominent components and facilitate tumor growth. The exact molecular …

Dual-Site Förster Resonance Energy Transfer Route of Upconversion Nanoparticles-Based Brain-Targeted Nanotheranostic Boosts the Near-Infrared Phototherapy …

J Wang, P Shangguan, M Lin, L Fu, Y Liu, L Han… - ACS …, 2023 - ACS Publications
Glioblastoma multiforme (GBM) is the most common malignant brain tumor with low survival,
primarily due to the blood–brain barrier (BBB) and high infiltration. Upconversion …

β2-microglobulin maintains glioblastoma stem cells and induces M2-like polarization of tumor-associated macrophages

D Li, Q Zhang, L Li, K Chen, J Yang, D Dixit, RC Gimple… - Cancer Research, 2022 - AACR
Glioblastoma (GBM) is a complex ecosystem that includes a heterogeneous tumor
population and the tumor-immune microenvironment (TIME), prominently containing tumor …

Glioblastoma-associated microglia-derived exosomal circKIF18A promotes angiogenesis by targeting FOXC2

Y Jiang, J Zhao, J Xu, H Zhang, J Zhou, H Li, G Zhang… - Oncogene, 2022 - nature.com
Glioblastoma multiforme (GBM) is the most lethal primary tumor with active
neovascularization in the central nervous system. Studying the novel molecular mechanisms …

Arachidonic acid metabolism controls macrophage alternative activation through regulating oxidative phosphorylation in PPARγ dependent manner

M Xu, X Wang, Y Li, X Geng, X Jia, L Zhang… - Frontiers in …, 2021 - frontiersin.org
Macrophage polarization is mainly steered by metabolic reprogramming in the tissue
microenvironment, thus leading to distinct outcomes of various diseases. However, the role …

Hypoxia‐driven M2‐polarized macrophages facilitate cancer aggressiveness and temozolomide resistance in glioblastoma

G Zhang, X Tao, B Ji, J Gong - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
Hypoxia‐induced M2 phenotypes of tumor associated macrophages (TAMs) promote the
development and chemoresistance of multiple types of cancers, including glioblastoma …

A Brain‐Targeting NIR‐II Ferroptosis System: Effective Visualization and Oncotherapy for Orthotopic Glioblastoma

J Zhang, L Han, H Wu, Y Zhong… - Advanced …, 2023 - Wiley Online Library
Abstract Near‐infrared‐II (NIR‐II) ferroptosis activators offer promising potentials in in vivo
theranostics of deep tumors, such as glioma. However, most cases are nonvisual iron …

Realizing Kagome Band Structure in Two-Dimensional Kagome Surface States of (, Ho)

S Peng, Y Han, G Pokharel, J Shen, Z Li, M Hashimoto… - Physical review …, 2021 - APS
We report angle resolved photoemission experiments on a newly discovered family of
kagome metals RV 6 Sn 6 (R= Gd, Ho). Intrinsic bulk states and surface states of the …