Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Design, printing, and engineering of regenerative biomaterials for personalized bone healthcare

Z Jia, X Xu, D Zhu, Y Zheng - Progress in Materials Science, 2023 - Elsevier
Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications

J Li, C Wu, PK Chu, M Gelinsky - Materials Science and Engineering: R …, 2020 - Elsevier
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …

Recent progress in extrusion 3D bioprinting of hydrogel biomaterials for tissue regeneration: a comprehensive review with focus on advanced fabrication techniques

M Askari, MA Naniz, M Kouhi, A Saberi… - Biomaterials …, 2021 - pubs.rsc.org
Over the last decade, 3D bioprinting has received immense attention from research
communities for developing functional tissues. Thanks to the complexity of tissues, various …

Mechanical forces direct stem cell behaviour in development and regeneration

KH Vining, DJ Mooney - Nature reviews Molecular cell biology, 2017 - nature.com
Stem cells and their local microenvironment, or niche, communicate through mechanical
cues to regulate cell fate and cell behaviour and to guide developmental processes. During …

Modeling physiological events in 2D vs. 3D cell culture

K Duval, H Grover, LH Han, Y Mou… - …, 2017 - journals.physiology.org
Cell culture has become an indispensable tool to help uncover fundamental biophysical and
biomolecular mechanisms by which cells assemble into tissues and organs, how these …

Designing hydrogels for controlled drug delivery

J Li, DJ Mooney - Nature Reviews Materials, 2016 - nature.com
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Bioresponsive materials

Y Lu, AA Aimetti, R Langer, Z Gu - Nature Reviews Materials, 2016 - nature.com
Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …

[HTML][HTML] Bioactive hydrogels for bone regeneration

X Bai, M Gao, S Syed, J Zhuang, X Xu, XQ Zhang - Bioactive materials, 2018 - Elsevier
Bone self-healing is limited and generally requires external intervention to augment bone
repair and regeneration. While traditional methods for repairing bone defects such as …