Regulatory roles of RNA modifications in breast cancer

K Kumari, P Groza, F Aguilo - NAR cancer, 2021 - academic.oup.com
Collectively referred to as the epitranscriptome, RNA modifications play important roles in
gene expression control regulating relevant cellular processes. In the last few decades …

APOBEC-1 Complementation Factor: From RNA Binding to Cancer

L Wang, Q Cheng - Cancer Control, 2024 - journals.sagepub.com
Background APOBEC-1 complementation factor (A1CF) and Apolipoprotein B mRNA editing
enzyme, catalytic polypeptide-1 (APOBEC-1) constitute the minimal proteins necessary for …

Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells

Y Song, L Shao, Y Xue, X Ruan, X Liu, C Yang… - Journal of Experimental …, 2019 - Springer
Background Glioma is the most common and lethal type of malignant brain tumor.
Accumulating evidence has highlighted that RNA binding protein APOBEC1 …

Genetic alteration of mRNA editing enzyme APOBEC3B in the pathogenesis of ovarian endometriosis

V Balasubramanian, R Saravanan… - Reproductive …, 2024 - Elsevier
Research question What are the specific genetic alterations and associated network in
endometriotic cells responsible for the disease pathogenesis? Design Case control …

A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells

Y Liu, J Yang, D Weng, Y Xie - International Journal of Molecular …, 2024 - mdpi.com
Apobec-1 complementation factor (A1CF) functions as an RNA-binding cofactor for APO-
BEC1-mediated C-to-U conversion during RNA editing and as a hepatocyte-specific …

High APOBEC1 complementation factor expression positively modulates the proliferation, invasion, and migration of endometrial cancer cells through regulating P53 …

Q Liu, CY Chen, GL Chen - Cancer biotherapy & …, 2022 - liebertpub.com
Background: APOBEC1 complementation factor (A1CF) is a component of the
apolipoprotein-B messenger RNA editing complex that participates in various cellular …

APOBEC1 complementation factor facilitates cell migration by promoting nucleus translocation of SMAD3 in renal cell carcinoma cells

H Xia, Y Liu, L Xu, H Mao, Q Zhou, Y Xie - In Vitro Cellular & …, 2021 - Springer
Metastasis is inevitable in about 30% of patients with primary renal cell carcinoma after
nephrectomy treatment. APOBEC1 complementation factor (A1CF), an RNA binding protein …