The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

Highlights•Increased emphasis in recent years on drugs targeting the endocannabinoid
system.•Recent discoveries about the role of the endocannabinoid system are …

Cannabis sativa has long been used for medicinal purposes. To improve safety and efficacy,
compounds from C. sativa were purified or synthesized and named under an umbrella group …

The cannabinoid type 1 (CB1) receptor is widely distributed in the brain and peripheral
organs where it regulates cellular functions and metabolism. In the brain, CB1 is mainly …

Abstract Astroglial type‐1 cannabinoid (CB1) receptors are involved in synaptic
transmission, plasticity and behavior by interfering with the so‐called tripartite synapse …

The type-1 cannabinoid receptor (CB1) is the main effector of the endocannabinoid system
(ECS), which is involved in most brain and body functions. In this Perspective, we provide …

The cannabinoid system is ubiquitously present and is classically considered to engage in
neural and immunity processes. Yet, the role of the cannabinoid system in the whole body …

The endocannabinoid system (ECS) controls energy balance by regulating both energy
intake and energy expenditure. Endocannabinoid levels are elevated in obesity suggesting …

Cardiovascular disease (CVD) is a global epidemic representing the leading cause of death
in some Western countries. According to the American Heart Association, a total of 92.1 …

The endocannabinoid system (ECS) is abundantly expressed in the brain. This system
regulates a plethora of physiological functions and is composed of cannabinoid receptors …