Presently, breast cancer (BC) is one of the most common malignancies diagnosed and the
leading cause of tumor-related deaths among women worldwide. Cell cycle dysregulation is …

The immune system plays a vital role in suppressing tumor cell progression. The tumor
microenvironment augmented with significant levels of tumor-infiltrating lymphocytes has …

Cell cycle dysregulation is a characteristic hallmark of malignancies, which results in
uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 …

Tumor heterogeneity is a hallmark of cancer and one of the primary causes of resistance to
therapies. Triple-negative breast cancer (TNBC), which accounts for 15–20% of all breast …

Adenocarcinoma is a common type of malignant tumor, originating from glandular epithelial
cells in various organs, such as pancreas, breast, lung, stomach, colon, rectus, and prostate …

Breast cancer is the leading cause of death among women worldwide. Despite the recent
treatment options like surgery, chemotherapy etc. the lethality of breast cancer is alarming …

Doxorubicin is a commonly used chemotherapeutic agent to treat several malignancies,
including aggressive tumors like triple-negative breast cancer. It has a limited therapeutic …

Background Baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, member of the
inhibitor of apoptosis (IAP), is a multitasking protein and among the top 100 deregulated …

Although advances in diagnostics and therapeutics have prolonged the survival of triple-
negative breast cancer (TNBC) patients, metastasis, therapeutic resistance, and lack of …

Breast cancer represents the leading cause of mortality among women worldwide. Since the
complexity of breast cancer as a disease resides in its heterogeneity as it consists of several …