For nearly 50 years the proximal tubule (PT) has been known to reabsorb, process, and
either catabolize or transcytose albumin from the glomerular filtrate. Innovative techniques …

Cells rely on the endoplasmic reticulum (ER) to fold and assemble newly synthesized
transmembrane and secretory proteins—essential for cellular structure–function and for both …

Liquid droplet has emerged as a flexible intracellular compartment that modulates various
cellular processes. Here, we uncover an antimetastatic mechanism governed by the liquid …

Abstract ZrO 2-Al 2 O 3 bioceramics have potential applications in the field of all-ceramic
restorations due to its excellent mechanical properties and biocompatibility. In this paper …

Mucopolysaccharidoses (MPSs) constitute a heterogeneous group of lysosomal storage
disorders characterized by the lysosomal accumulation of glycosaminoglycans (GAGs) …

Lysosomes play a central role in cellular homeostasis and alterations in this compartment
associate with many diseases. The most studied example is that of lysosomal storage …

Archaea are microorganisms more closely related to eukaryotes than bacteria. Almost 50
years after being defined as a new domain of life on earth, new species continue to be …

Aberrant activation of RAS/MAPK signaling is common in cancer, and efforts to inhibit
pathway components have yielded drugs with promising clinical activities. Unfortunately …

The study of the molecular mechanisms of stress appraisal on farmed fish is paramount to
ensuring a sustainable aquaculture. Stress exposure can either culminate in the organism's …

Nanoparticles have become versatile assets in the medical field, providing notable benefits
across diverse medical arenas including controlled drug delivery, imaging, and …