Spherical crystallization of drugs

B Kovačič, F Vrečer, O Planinšek - Acta pharmaceutica, 2012 - sciendo.com
Spherical crystallization of drugs is the process of obtaining larger particles by
agglomeration during crystallization. The most common techniques used to obtain such …

[HTML][HTML] Spherical crystallization: A technique use to reform solubility and flow property of active pharmaceutical ingredients

A Chatterjee, MM Gupta… - International journal of …, 2017 - ncbi.nlm.nih.gov
Tablets have been choice of manufacturers over the years due to their comparatively low
cost of manufacturing, packaging, shipping, and ease of administration; also have better …

[HTML][HTML] Nicotinamide-based agglomerates of ibuprofen: formulation, solid state characterization and evaluation of tableting performance with in-silico investigation

PH Sidwadkar, NH Salunkhe, KK Mali… - Future Journal of …, 2023 - Springer
Background The objective of the present investigation was to obtain directly compressible
agglomerates of ibuprofen with nicotinamide by a quasi-emulsification solvent diffusion …

Influence of polymers/excipients on development of agglomerated crystals of secnidazole by crystallo-co-agglomeration technique to improve processability

MK Raval, KR Sorathiya, NP Chauhan… - Drug development …, 2013 - Taylor & Francis
Background: Direct tabletting is a need of Pharmaceutical industries. Poor mechanical
properties of drug particles require wet granulation which is uneconomical, laborious, and …

Particle design of drugs by spherical crystallization techniques

S Mahanty, J Sruti, NP Ch, BR ME - International Journal of …, 2010 - ijpsnonline.com
Direct tabletting technique is the most easy and simplest way of making tablets. Good
flowability and compressibility is prerequisite for drug to be prepared by direct compression …

[PDF][PDF] Talc: A versatile pharmaceutical excipient

NR Jadhav, AR Paradkar, NH Salunkhe… - World Journal of …, 2013 - researchgate.net
The present review highlights meticulous account of talc with respect to extraction from
mines, purification, pharmaceutical and other applications. Talc is a hydrous magnesium …

Preparation and evaluation of agglomerated crystals by crystallo-co-agglomeration: an integrated approach of principal component analysis and Box–Behnken …

KC Garala, JM Patel, AP Dhingani… - International journal of …, 2013 - Elsevier
Poor mechanical properties of crystalline drug particles require wet granulation technique
for tablet production which is uneconomical, laborious, and tedious. The present …

Crystallo-co-agglomeration: A novel particle engineering technique

AR Paradkar, AP Pawar - Asian Journal of Pharmaceutics …, 2010 - asiapharmaceutics.info
Abstract Crystallo-co-agglomeration (CCA) is a novel particle engineering/design technique
developed by Kadam et al, to overcome the limitations of spherical crystallization (SC) …

Tailoring of ketoprofen particle morphology via novel crystallocoagglomeration technique to obtain a directly compressible material

V Chavda, RK Maheshwari - Asian Journal of …, 2008 - asiapharmaceutics.info
Purpose: The purpose of this research was to develop a novel crystallo-co-agglomeration
(CCA) method for ketoprofen to obtain its directly compressible spherical agglomerates with …

Particle Size Enlargement: Making and Understanding of the Behavior of Powder (Particle) System.

VV Kale, S Gadekar… - Surgical Neurology …, 2011 - search.ebscohost.com
Particle size enlargement is the process of transforming fine particles into larger particles by
the introduction of external forces, and is a value-added step in many processes involving …