Exercise-stimulated glucose uptake—regulation and implications for glycaemic control
Skeletal muscle extracts glucose from the blood to maintain demand for carbohydrates as an
energy source during exercise. Such uptake involves complex molecular signalling …
energy source during exercise. Such uptake involves complex molecular signalling …
Exercise training and skeletal muscle antioxidant enzymes: An update
The pivotal observation that muscular exercise is associated with oxidative stress in humans
was first reported over 45 years ago. Soon after this landmark finding, it was discovered that …
was first reported over 45 years ago. Soon after this landmark finding, it was discovered that …
Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex
Reactive oxygen species (ROS) contribute to the development of non-alcoholic fatty liver
disease. ROS generation by infiltrating macrophages involves multiple mechanisms …
disease. ROS generation by infiltrating macrophages involves multiple mechanisms …
Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise
C Henríquez-Olguin, JR Knudsen, SH Raun… - Nature …, 2019 - nature.com
Reactive oxygen species (ROS) act as intracellular compartmentalized second messengers,
mediating metabolic stress-adaptation. In skeletal muscle fibers, ROS have been suggested …
mediating metabolic stress-adaptation. In skeletal muscle fibers, ROS have been suggested …
Dissecting redox biology using fluorescent protein sensors
Significance: Fluorescent protein sensors have revitalized the field of redox biology by
revolutionizing the study of redox processes in living cells and organisms. Recent Advances …
revolutionizing the study of redox processes in living cells and organisms. Recent Advances …
Reactive oxygen species and redox compartmentalization
N Kaludercic, S Deshwal, F Di Lisa - Frontiers in physiology, 2014 - frontiersin.org
Reactive oxygen species (ROS) formation and signaling are of major importance and
regulate a number of processes in physiological conditions. A disruption in redox status …
regulate a number of processes in physiological conditions. A disruption in redox status …
Src-dependent impairment of autophagy by oxidative stress in a mouse model of Duchenne muscular dystrophy
R Pal, M Palmieri, JA Loehr, S Li, R Abo-Zahrah… - Nature …, 2014 - nature.com
Duchenne muscular dystrophy (DMD) is a fatal degenerative muscle disease resulting from
mutations in the dystrophin gene. Increased oxidative stress and altered Ca2+ homeostasis …
mutations in the dystrophin gene. Increased oxidative stress and altered Ca2+ homeostasis …
Molecular basis for exercise-induced fatigue: the importance of strictly controlled cellular Ca2+ handling
The contractile function of skeletal muscle declines during intense or prolonged physical
exercise, that is, fatigue develops. Skeletal muscle fibers fatigue acutely during highly …
exercise, that is, fatigue develops. Skeletal muscle fibers fatigue acutely during highly …
Regulation of NADPH oxidases in skeletal muscle
LF Ferreira, O Laitano - Free Radical Biology and Medicine, 2016 - Elsevier
The only known function of NAD (P) H oxidases is to produce reactive oxygen species
(ROS). Skeletal muscles express three isoforms of NAD (P) H oxidases (Nox1, Nox2, and …
(ROS). Skeletal muscles express three isoforms of NAD (P) H oxidases (Nox1, Nox2, and …
Reactive oxygen/nitrogen species and contractile function in skeletal muscle during fatigue and recovery
AJ Cheng, T Yamada, DE Rassier… - The Journal of …, 2016 - Wiley Online Library
The production of reactive oxygen/nitrogen species (ROS/RNS) is generally considered to
increase during physical exercise. Nevertheless, direct measurements of ROS/RNS often …
increase during physical exercise. Nevertheless, direct measurements of ROS/RNS often …