Several promising strategies based on combining or cycling different antibiotics have been
proposed to increase efficacy and counteract resistance evolution, but we still lack a deep …

Multistability or coexistence of different attractors for a given set of parameters is one of the
most exciting phenomena in dynamical systems. It can be found in different areas of science …

Memristor-based nonlinear dynamical system easily presents the initial condition-dependent
dynamical phenomenon of extreme multistability, ie, coexisting infinitely many attractors …

Many systems on our planet shift abruptly and irreversibly from the desired state to an
undesired state when forced across a “tipping point”. Some examples are mass extinctions …

The genetic circuits that regulate cellular functions are subject to stochastic fluctuations, or
'noise', in the levels of their components. Noise, far from just a nuisance, has begun to be …

Heritability has traditionally been thought to be a characteristic feature of the genetic
material of an organism—notably, its DNA. However, it is now clear that inheritance not …

Gene expression is a fundamentally stochastic process, with randomness in transcription
and translation leading to cell-to-cell variations in mRNA and protein levels. This variation …

Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

For microbiome biology to become a more predictive science, we must identify which
descriptive features of microbial communities are reproducible and predictable, which are …

Genetically identical cells exposed to the same environmental conditions can show
significant variation in molecular content and marked differences in phenotypic …