The potential role of miRNAs in the pathogenesis of testicular germ cell tumors-A Focus on signaling pathways interplay

AS Doghish, HAM Moustafa, MS Elballal… - … -Research and Practice, 2023 - Elsevier
Testicular germ cell tumors (TGCTs) are the most common testicular neoplasms in
adolescents and young males. Understanding the genetic basis of TGCTs represents a …

A systematic review of the research progress of non-coding RNA in neuroinflammation and immune regulation in cerebral infarction/ischemia-reperfusion injury

K Yang, L Zeng, A Ge, S Wang, J Zeng, X Yuan… - Frontiers in …, 2022 - frontiersin.org
Cerebral infarction/ischemia-reperfusion injury is currently the disease with the highest
mortality and disability rate of cardiovascular disease. Current studies have shown that …

Circulating microRNAs as potential biomarkers in pancreatic cancer—advances and challenges

AA Seyhan - International journal of molecular sciences, 2023 - mdpi.com
There is an urgent unmet need for robust and reliable biomarkers for early diagnosis,
prognosis, and prediction of response to specific treatments of many aggressive and deadly …

Atherosclerosis, diabetes mellitus, and cancer: common epidemiology, shared mechanisms, and future management

V Katsi, I Papakonstantinou, K Tsioufis - International Journal of …, 2023 - mdpi.com
The involvement of cardiovascular disease in cancer onset and development represents a
contemporary interest in basic science. It has been recognized, from the most recent …

CRISPR/Cas13a‐Based MicroRNA detection in tumor‐derived extracellular vesicles

JS Hong, T Son, CM Castro, H Im - Advanced Science, 2023 - Wiley Online Library
MicroRNAs (miRNAs) in extracellular vesicles (EVs) play essential roles in cancer initiation
and progression. Quantitative measurements of EV miRNAs are critical for cancer diagnosis …

Macrophage‐derived exosomal miR‐4532 promotes endothelial cells injury by targeting SP1 and NF‐κB P65 signalling activation

P Liu, S Wang, G Wang, M Zhao, F Du… - Journal of cellular …, 2022 - Wiley Online Library
Atherosclerosis is a complex pathological process involving macrophages, endothelial cells
and vascular smooth muscle cells that can lead to ischemic heart disease; however, the …

Obesity and leukemia: biological mechanisms, perspectives, and challenges

D Tsilingiris, NG Vallianou, N Spyrou… - Current Obesity …, 2024 - Springer
Abstract Purpose of Review To examine the epidemiological data on obesity and leukemia;
evaluate the effect of obesity on leukemia outcomes in childhood acute lymphoblastic …

Role of miR-21 in the diagnosis of colorectal cancer: Meta-analysis and bioinformatics

J Li, H Chen, G Sun, X Zhang, H Ye, P Wang - Pathology-Research and …, 2023 - Elsevier
Advanced colorectal cancer (CRC) has a bad prognosis and is challenging to cure.
Therefore, there is an urgent need for an effective early diagnosis marker. MicroRNA-21 …

[HTML][HTML] The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancer

Z Wang, W Xie, H Guan - Biomedicine & Pharmacotherapy, 2023 - Elsevier
MicroRNA are non-coding small RNAs that bind to their target mRNA and cause mRNA
degradation or translation inhibition. MiRNA dysregulation is linked to a variety of human …

Proteomic analyses reveal new features of the box H/ACA RNP biogenesis

F Schlotter, S Mérouani, J Flayac, V Kogey… - Nucleic Acids …, 2023 - academic.oup.com
Abstract The conserved H/ACA RNPs consist of one H/ACA RNA and 4 core proteins:
dyskerin, NHP2, NOP10, and GAR1. Its assembly requires several assembly factors. A pre …