The role of gastric mucosal immunity in gastric diseases

S Nie, Y Yuan - Journal of Immunology Research, 2020 - Wiley Online Library
Gastric mucosa plays its immune function through innate and adaptive immunity by
recruiting immune cells and releasing corresponding cytokines, which have an inseparable …

Host–microbiota interplay in mediating immune disorders

KM Felix, S Tahsin, HJJ Wu - Annals of the New York Academy …, 2018 - Wiley Online Library
To maintain health, the immune system must maintain a delicate balance between
eliminating invading pathogens and avoiding immune disorders such as autoimmunity and …

Helicobacter pylori Colonization Is Inversely Associated with Childhood Asthma

Y Chen, MJ Blaser - The Journal of infectious diseases, 2008 - academic.oup.com
Background. Asthma, a serious health problem worldwide, is becoming more common.
Colonization with Helicobacter pylori, a major human indigenous (commensal) microbe …

Does Helicobacter pylori protect against asthma and allergy?

MJ Blaser, Y Chen, J Reibman - Gut, 2008 - gut.bmj.com
The microbes that persistently colonise their vertebrate hosts are not accidental. 1 Although
highly numerous and diverse, there is specificity by site and substantial conservation …

Helicobacter pylori Infection Significantly Increases Insulin Resistance in the Asymptomatic Japanese Population

T Gunji, N Matsuhashi, H Sato, K Fujibayashi… - …, 2009 - Wiley Online Library
Background: Helicobacter pylori infection has been shown to contribute to atherosclerosis
and cardiovascular diseases. Insulin resistance is the pathophysiologic background of the …

Helicobacter pylori infection associated with high HbA1c and type 2 diabetes

MC Hsieh, SSW Wang, YT Hsieh… - European journal of …, 2013 - Wiley Online Library
Background Although the association between chronic H elicobacter pylori infection and
type 2 diabetes has been suggested, findings have been inconsistent. This study evaluated …

Helicobacter Pylori Infection is Positively Associated with Metabolic Syndrome in Taiwanese Adults: a Cross‐Sectional Study

TP Chen, HF Hung, MK Chen, HH Lai, WF Hsu… - …, 2015 - Wiley Online Library
Background Helicobacter pylori infection and metabolic syndrome have been reported to be
positively associated. However, only a few studies have focused on this issue, and H. pylori …

Helicobacter pylori infection, chronic atrophic gastritis and major cardiovascular events: a population-based cohort study

B Schöttker, MA Adamu, MN Weck, H Müller, H Brenner - Atherosclerosis, 2012 - Elsevier
OBJECTIVE: There is debate whether infection with Helicobacter (H.) pylori, the main
inducer of chronic atrophic gastritis (CAG), is a risk factor for cardiovascular disease and …

CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice

MS Alam, CC Kurtz, RM Rowlett… - The Journal of …, 2009 - academic.oup.com
Background. Regulatory T cells (known as “Treg”) express apyrases (CD39) and ecto-5'-
nucleotidase (CD73) and contribute to their inhibitory function by generating adenosine. We …

Influence of functional polymorphisms in TNF-α, IL-8, and IL-10 cytokine genes on mRNA expression levels and risk of gastric cancer

JG de Oliveira, AFT Rossi, DM Nizato, ACT Cadamuro… - Tumor Biology, 2015 - Springer
Functional polymorphisms in promoter regions can produce changes in the affinity of
transcription factors, thus altering the messenger ribonucleic acid (mRNA) expression levels …