Pyridines and Imidazopyridines with medicinal significance
T LS Kishbaugh - Current Topics in Medicinal Chemistry, 2016 - ingentaconnect.com
Pyridine and pyridine-fused ring systems are ubiquitous in medicinal research and
demonstrate such diverse pharmacological benefits as anticonvulsant therapies, treatment …
demonstrate such diverse pharmacological benefits as anticonvulsant therapies, treatment …
Pharmacological Potential and Synthetic Approaches of Imidazo[4,5-b]pyridine and Imidazo[4,5-c]pyridine Derivatives
M Krause, H Foks, K Gobis - Molecules, 2017 - mdpi.com
The structural resemblance between the fused imidazopyridine heterocyclic ring system and
purines has prompted biological investigations to assess their potential therapeutic …
purines has prompted biological investigations to assess their potential therapeutic …
Synthesis of coumarins linked with 1, 2, 3-triazoles under microwave irradiation and evaluation of their antimicrobial and antioxidant activity
M Nibin Joy, YD Bodke, S Telkar… - Journal of the Mexican …, 2020 - scielo.org.mx
A series of coumarin derivatives linked with 1, 2, 3-triazoles has been synthesized by
utilizing the copper catalyzed azide-alkyne cycloaddition reaction and were screened for …
utilizing the copper catalyzed azide-alkyne cycloaddition reaction and were screened for …
Novel amino substituted tetracyclic imidazo [4, 5-b] pyridine derivatives: Design, synthesis, antiproliferative activity and DNA/RNA binding study
A novel series of tetracyclic imidazo [4, 5-b] pyridine derivatives was designed and
synthesized as potential antiproliferative agents. Their antiproliferative activity against …
synthesized as potential antiproliferative agents. Their antiproliferative activity against …
Two-photon brightness of highly fluorescent imidazopyridine derivatives: Two-photon and ultrafast transient absorption studies
Imidazopyridine derivatives are unnatural purines isosteres and have been idealized and
synthesized in the last decades, given their great applicability in several science areas. For …
synthesized in the last decades, given their great applicability in several science areas. For …
Design, synthesis, and biological evaluation of imidazopyridine‐linked thiazolidinone as potential anticancer agents
In this study, two series of imidazopyridine‐linked thiazolidinone rings (5a–h and 6a–h)
constituting 16 new compounds were synthesized and tested for their antiproliferative …
constituting 16 new compounds were synthesized and tested for their antiproliferative …
Novel tacrine derivatives exhibiting improved acetylcholinesterase inhibition: Design, synthesis and biological evaluation
A novel series of twenty four tacrine derivatives were designed and synthesised. Among
these, thirteen were taken for the acetylcholinesterase (AChE) inhibition studies. Three …
these, thirteen were taken for the acetylcholinesterase (AChE) inhibition studies. Three …
Functionalised dihydroazo pyrimidine derivatives from Morita–Baylis–Hillman acetates: synthesis and studies against acetylcholinesterase as its inhibitors
A wide array of dihydro [1, 5] azo [1, 2-a] pyrimidine 2-esters have been synthesised at room
temperature in moderate to good yields through one-pot reaction between nitrostyrene …
temperature in moderate to good yields through one-pot reaction between nitrostyrene …
Separation of ephedrine and pseudoephedrine enantiomers using a polysaccharide‐based chiral column: a normal phase liquid chromatography–high‐resolution …
AK Karakka Kal, TK Karatt, R Sayed, M Philip… - Chirality, 2019 - Wiley Online Library
Chiral considerations are found to be very much relevant in various aspects of forensic
toxicology and pharmacology. In forensics, it has become increasingly important to identify …
toxicology and pharmacology. In forensics, it has become increasingly important to identify …
Microwave-assisted synthesis of certain pyrrolylpyridines, some derived ring systems and their evaluation as anticancer and antioxidant agents
SAF Rostom, AA Bekhit - European Journal of Medicinal Chemistry, 2015 - Elsevier
The synthesis of 18 novel pyrrolylpyridines and some derived bi-, tri-and tetracyclic ring
systems using both the conventional heating and MW irradiation techniques is described …
systems using both the conventional heating and MW irradiation techniques is described …