Background: Postsurgical pain is a key component of surgical recovery. However, the
genetic drivers of postsurgical pain remain unclear. A broad review and meta-analyses of …

Opioids are a mainstay of treatment for pain worldwide. Pruritus, a common side effect of
opioids, is a patient dissatisfier that limits their use in many clinical settings. Both parenteral …

Background: Responsiveness to opioid analgesics differs among patients with acute
postoperative pain. Objective: Our study presents the most recent evidence on the effect of …

Background: There is obvious difference in individual response to opioids. Many studies
have examined the correlation between the μ-opioid receptor 1 (OPRM1) 118A> G genetic …

Objective Several studies have attempted to identify genetic determinants of clinical
response to opioids administered during labor or after cesarean section. However, their …

This paper is the forty-first consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Aim: This systematic review aimed to outline the outcome of OPRMI (A118G) variants on the
effects of anesthetic and analgesic agents used in various procedures. Materials & methods …

Incidence and risk factors for epidural morphine induced pru... : Medicine Incidence and risk
factors for epidural morphine induced pruritus in parturients receiving cesarean section: A …

Pharmacogenomics (PGx) implementation has become increasingly widespread. One of the
most important aspects of this implementation process is the development of appropriate …

Substance use disorders (SUDs) are a group of neuropsychiatric conditions manifesting due
to excessive dependence on potential drugs of abuse such as psychostimulants, opioids …