The immunomodulation and anti-inflammatory effects of garlic organosulfur compounds in cancer chemoprevention

G Schafer, CH Kaschula - Anti-Cancer Agents in Medicinal …, 2014 - ingentaconnect.com
Garlic (Allium sativum) has been used for centuries as a prophylactic and therapeutic
medicinal agent. Importantly, garlic has been suggested to have both cancer-preventive …

Therapeutic potential of plants and plant derived phytochemicals against acetaminophen-induced liver injury

SB Subramanya, B Venkataraman… - International journal of …, 2018 - mdpi.com
Acetaminophen (APAP), which is also known as paracetamol or N-acetyl-p-aminophenol is
a safe and potent drug for fever, pain and inflammation when used at its normal therapeutic …

Comparison of cytotoxicity evaluation of anticancer drugs between real-time cell analysis and CCK-8 method

L Cai, X Qin, Z Xu, Y Song, H Jiang, Y Wu, H Ruan… - ACS …, 2019 - ACS Publications
Critical cytotoxicity evaluation of pharmaceuticals is necessary for the clinical practice of
chemotherapy. To quantitatively evaluate cell viability, currently there are two main types of …

The role of tumor microenvironment in chemoresistance: 3D extracellular matrices as accomplices

DA Senthebane, T Jonker, A Rowe… - International journal of …, 2018 - mdpi.com
Background: The functional interplay between tumor cells and their adjacent stroma has
been suggested to play crucial roles in the initiation and progression of tumors and the …

Sulfur–sulfur bond construction

M Wang, X Jiang - Sulfur Chemistry, 2019 - Springer
Disulfide, as a common structural motif, has been frequently used in pharmaceuticals, nature
products, and chemical biology. This chapter focuses on the methodologies that were …

Allicin and digestive system cancers: from chemical structure to its therapeutic opportunities

M Sarvizadeh, O Hasanpour… - Frontiers in …, 2021 - frontiersin.org
Digestive system cancer tumors are one of the major causes of cancer-related fatalities; the
vast majority of them are colorectal or gastric malignancies. Epidemiological evidence …

[HTML][HTML] Aged black garlic extract inhibits HT29 colon cancer cell growth via the PI3K/Akt signaling pathway

M Dong, G Yang, H Liu, X Liu, S Lin… - Biomedical …, 2014 - spandidos-publications.com
Accumulating evidence indicates that aged black garlic extract (ABGE) may prove beneficial
in preventing or inhibiting oncogenesis; however, the underlying mechanisms have not …

Allicin in digestive system cancer: from biological effects to clinical treatment

Y Zhou, X Li, W Luo, J Zhu, J Zhao, M Wang… - Frontiers in …, 2022 - frontiersin.org
Allicin is the main active ingredient in freshly-crushed garlic and some other allium plants,
and its anticancer effect on cancers of digestive system has been confirmed in many studies …

The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells

CH Kaschula, R Tuveri, E Ngarande, K Dzobo… - BMC cancer, 2019 - Springer
Background Garlic has been used for centuries for its flavour and health promoting
properties that include protection against cancer. The vinyl disulfide-sulfoxide ajoene is one …

Recent developments in the synthesis of unsymmetrical disulfanes (disulfides). A review

M Musiejuk, D Witt - Organic Preparations and Procedures …, 2015 - Taylor & Francis
Compounds with the structure RSSR, where the R group can be alkyl, vinyl or aryl are
termed disulfides and symmetrical disufides when the R groups are the same …