A review of central 5-HT receptors and their function
NM Barnes, T Sharp - Neuropharmacology, 1999 - Elsevier
It is now nearly 5 years since the last of the currently recognised 5-HT receptors was
identified in terms of its cDNA sequence. Over this period, much effort has been directed …
identified in terms of its cDNA sequence. Over this period, much effort has been directed …
5-HT3 receptors
AJ Thompson, SC R Lummis - Current pharmaceutical design, 2006 - ingentaconnect.com
The 5-HT3 receptor is a member of the Cys-loop family of ligand-gated ion channels. These
receptors are located in both the peripheral and central nervous systems, where functional …
receptors are located in both the peripheral and central nervous systems, where functional …
[HTML][HTML] Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs
E Dale, B Bang-Andersen, C Sánchez - Biochemical pharmacology, 2015 - Elsevier
The monoamine hypothesis has been the prevailing hypothesis of depression over the last
several decades. It states that depression is associated with reduced monoamine function …
several decades. It states that depression is associated with reduced monoamine function …
Serotonin receptors in hippocampus
Serotonin is an ancient molecular signal and a recognized neurotransmitter brainwide
distributed with particular presence in hippocampus. Almost all serotonin receptor subtypes …
distributed with particular presence in hippocampus. Almost all serotonin receptor subtypes …
The 5-HT3 receptor as a therapeutic target
AJ Thompson, SCR Lummis - Expert opinion on therapeutic targets, 2007 - Taylor & Francis
The 5-HT3 receptor is a neurotransmitter-gated ion channel. It is a member of the Cys-loop
family of receptors, which also includes nicotinic acetylcholine, glycine and GABAA …
family of receptors, which also includes nicotinic acetylcholine, glycine and GABAA …
5-HT3 receptors mediate serotonergic fast synaptic excitation of neocortical vasoactive intestinal peptide/cholecystokinin interneurons
Neocortical neurons expressing the serotonin 5-HT3receptor (5-HT3R) were characterized
in rat acute slices by using patch-clamp recordings combined with single-cell RT-PCR and …
in rat acute slices by using patch-clamp recordings combined with single-cell RT-PCR and …
The pharmacological and functional characteristics of the serotonin 5-HT3A receptor are specifically modified by a 5-HT3B receptor subunit
AE Dubin, R Huvar, MR D'Andrea, J Pyati… - Journal of Biological …, 1999 - ASBMB
While homomers containing 5-HT 3A subunits form functional ligand-gated serotonin (5-HT)
receptors in heterologous expression systems (Jackson, MB, and Yakel, JL (1995) Annu …
receptors in heterologous expression systems (Jackson, MB, and Yakel, JL (1995) Annu …
Localization of agonist and competitive antagonist binding sites on nicotinic acetylcholine receptors
HR Arias - Neurochemistry international, 2000 - Elsevier
Identification of all residues involved in the recognition and binding of cholinergic ligands
(eg agonists, competitive antagonists, and noncompetitive agonists) is a primary objective to …
(eg agonists, competitive antagonists, and noncompetitive agonists) is a primary objective to …
The molecular basis of the structure and function of the 5-HT 3 receptor: a model ligand-gated ion channel
DC Reeves, SCR Lummis - Molecular membrane biology, 2002 - Taylor & Francis
The ligand-gated ion channel superfamily of neurotransmitter receptors are proteins
responsible for rapid transmission of nerve impulses at the synapse and have, therefore …
responsible for rapid transmission of nerve impulses at the synapse and have, therefore …
5-HT3 receptors and the neural actions of alcohols: an increasingly exciting topic
DM Lovinger - Neurochemistry international, 1999 - Elsevier
The 5-HT3 receptor is a ligand-gated ion channel activated by the neurotransmitter
serotonin. Receptors of this subtype have been localized to several regions of the brain, and …
serotonin. Receptors of this subtype have been localized to several regions of the brain, and …