Patient and disease–specific induced pluripotent stem cells for discovery of personalized cardiovascular drugs and therapeutics
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for
regenerative therapy, disease modeling, and drug discovery. iPSCs allow for the production …
regenerative therapy, disease modeling, and drug discovery. iPSCs allow for the production …
Hydrogels for large-scale expansion of stem cells
S Yin, Y Cao - Acta biomaterialia, 2021 - Elsevier
Stem cells demonstrate considerable promise for various preclinical and clinical
applications, including drug screening, disease treatments, and regenerative medicine …
applications, including drug screening, disease treatments, and regenerative medicine …
[HTML][HTML] Bioscaffolds embedded with regulatory modules for cell growth and tissue formation: A review
P Wang, Y Sun, X Shi, H Shen, H Ning, H Liu - Bioactive Materials, 2021 - Elsevier
The demand for artificial organs has greatly increased because of various aging-associated
diseases and the wide need for organ transplants. A recent trend in tissue engineering is the …
diseases and the wide need for organ transplants. A recent trend in tissue engineering is the …
Tailoring hydrogel composition and stiffness to control smooth muscle cell differentiation in bioprinted constructs
Background: Reliable in vitro cellular models are needed to study the phenotypic
modulation of smooth muscle cells (SMCs) in health and disease. The aim of this study was …
modulation of smooth muscle cells (SMCs) in health and disease. The aim of this study was …
Insights on three dimensional organoid studies for stem cell therapy in regenerative medicine
Regenerative medicine has developed as a promising discipline that utilizes stem cells to
address limitations in traditional therapies, using innovative techniques to restore and repair …
address limitations in traditional therapies, using innovative techniques to restore and repair …
Alginate microfibers as therapeutic delivery scaffolds and tissue mimics
Y Xie, SCR Kollampally… - … Biology and Medicine, 2022 - journals.sagepub.com
Alginate, a naturally occurring polysaccharide, has been widely used in cell encapsulation,
3D culture, cell therapy, tissue engineering, and regenerative medicine. Alginate's frequent …
3D culture, cell therapy, tissue engineering, and regenerative medicine. Alginate's frequent …
Hydrogels: A potential platform for induced pluripotent stem cell culture and differentiation
Induced pluripotent stem cells (iPSCs) can be used to generate desired types of cells that
belong to the three germ layers (ie, ectoderm, endoderm and mesoderm). These cells …
belong to the three germ layers (ie, ectoderm, endoderm and mesoderm). These cells …
[HTML][HTML] Fabricating 3-dimensional human brown adipose microtissues for transplantation studies
Transplanting cell cultured brown adipocytes (BAs) represents a promising approach to
prevent and treat obesity (OB) and its associated metabolic disorders, including type 2 …
prevent and treat obesity (OB) and its associated metabolic disorders, including type 2 …
Electrospun fibre diameter and its effects on vascular smooth muscle cells
JA Reid, A McDonald, A Callanan - Journal of Materials Science: Materials …, 2021 - Springer
Bypass grafting is a technique used in the treatment of vascular disease, which is currently
the leading cause of mortality worldwide. While technology has moved forward over the …
the leading cause of mortality worldwide. While technology has moved forward over the …
Generation of a purified iPSC-derived smooth muscle-like population for cell sheet engineering
Induced pluripotent stem cells (iPSCs) provide a potential source for the derivation of
smooth muscle cells (SMCs); however, current approaches are limited by the production of …
smooth muscle cells (SMCs); however, current approaches are limited by the production of …