The gut–brain axis and its relation to Parkinson's disease: a review

EM Klann, U Dissanayake, A Gurrala… - Frontiers in aging …, 2022 - frontiersin.org
Parkinson's disease is a chronic neurodegenerative disease characterized by the
accumulation of misfolded alpha-synuclein protein (Lewy bodies) in dopaminergic neurons …

Oxidative stress in Parkinson's disease: Potential benefits of antioxidant supplementation

S Percário, A da Silva Barbosa… - Oxidative medicine …, 2020 - Wiley Online Library
Parkinson's disease (PD) occurs in approximately 1% of the population over 65 years of age
and has become increasingly more common with advances in age. The number of …

Biomarkers for Parkinson's disease: how good are they?

T Li, W Le - Neuroscience bulletin, 2020 - Springer
Parkinson's disease (PD) is a complex neurodegenerative disorder with no cure in sight.
Clinical challenges of the disease include the inability to make a definitive diagnosis at the …

Implications of the gut microbiome in Parkinson's disease

M Elfil, S Kamel, M Kandil, BB Koo… - Movement …, 2020 - Wiley Online Library
Parkinson's disease is a common neurodegenerative disorder that presents with nonmotor
and motor symptoms. The nonmotor manifestations of Parkinson's disease often begin years …

An exosomal urinary miRNA signature for early diagnosis of renal fibrosis in lupus nephritis

C Solé, T Moliné, M Vidal, J Ordi-Ros… - Cells, 2019 - mdpi.com
For lupus nephritis (LN) management, it is very important to detect fibrosis at an early stage.
Urinary exosomal miRNAs profiling can be used as a potential multi-marker phenotyping …

DAT and TH expression marks human Parkinson's disease in peripheral immune cells

A Gopinath, P Mackie, B Hashimi, AM Buchanan… - npj Parkinson's …, 2022 - nature.com
Parkinson's disease (PD) is marked by a loss of dopamine neurons, decreased dopamine
transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation …

Blood-based biomarker in Parkinson's disease: potential for future applications in clinical research and practice

L Tönges, C Buhmann, S Klebe, J Klucken… - Journal of Neural …, 2022 - Springer
The clinical presentation of Parkinson's disease (PD) is both complex and heterogeneous,
and its precise classification often requires an intensive work-up. The differential diagnosis …

Point‐of‐care detection of cytokines in cytokine storm management and beyond: Significance and challenges

G Liu, C Jiang, X Lin, Y Yang - View, 2021 - Wiley Online Library
Cytokines are signaling molecules between cells in immune system. Cytokine storm, due to
the sudden acute increase in levels of pro‐inflammatory circulating cytokines, can result in …

Blood and cerebrospinal fluid biomarkers of inflammation in Parkinson's disease

M Zimmermann, K Brockmann - Journal of Parkinson's …, 2022 - content.iospress.com
Given the clear role of inflammation in the pathogenesis of Parkinson's disease (PD) and its
impact on incidence and phenotypical characteristics, this review provides an overview with …

Parkinson's disease: a systemic inflammatory disease accompanied by bacterial inflammagens

B Adams, JM Nunes, MJ Page, T Roberts… - Frontiers in aging …, 2019 - frontiersin.org
Parkinson's disease (PD) is a well-known neurodegenerative disease with a strong
association established with systemic inflammation. Recently, the role of the gingipain …