[HTML][HTML] Ancient genomes reveal structural shifts after the arrival of Steppe-related ancestry in the Italian Peninsula

T Saupe, F Montinaro, C Scaggion, N Carrara… - Current Biology, 2021 - cell.com
Across Europe, the genetics of the Chalcolithic/Bronze Age transition is increasingly
characterized in terms of an influx of Steppe-related ancestry. The effect of this major shift on …

Racial differences in immunological landscape modifiers contributing to disparity in prostate cancer

J King Thomas, H Mir, N Kapur, S Singh - Cancers, 2019 - mdpi.com
Prostate cancer affects African Americans disproportionately by exhibiting greater incidence,
rapid disease progression, and higher mortality when compared to their Caucasian …

IL-19 as a potential therapeutic in autoimmune and inflammatory diseases

YT Azuma, H Nakajima… - Current pharmaceutical …, 2011 - ingentaconnect.com
Interleukin-19 (IL-19) is a member of the IL-10 family of cytokines. The last ten years from the
finding of IL-19, investigations underline the role of IL-19 in the immunological diseases. It is …

Genetic history of Cambridgeshire before and after the Black Death

R Hui, CL Scheib, E D'Atanasio, SA Inskip… - Science …, 2024 - science.org
The extent of the devastation of the Black Death pandemic (1346–1353) on European
populations is known from documentary sources and its bacterial source illuminated by …

Inflammatory profile of vertically HIV-1 infected adolescents receiving ART in Cameroon: a contribution toward optimal pediatric HIV control strategies

AC Ka'e, AJ Nanfack, G Ambada, MM Santoro… - Frontiers in …, 2023 - frontiersin.org
Antiretroviral therapy (ART) has improved the lifespan of people living with HIV. However,
their immune system remains in a state of sustained activation/inflammation, which favors …

P2X antagonists inhibit HIV-1 productive infection and inflammatory cytokines interleukin-10 (IL-10) and IL-1β in a human tonsil explant model

AY Soare, ND Durham, R Gopal, B Tweel… - Journal of …, 2019 - Am Soc Microbiol
ABSTRACT HIV-1 causes a persistent infection of the immune system that is associated with
chronic comorbidities. The mechanisms that underlie this inflammation are poorly …

Host Genetic Impact on Infectious Diseases among Different Ethnic Groups

L Naidoo, T Arumugam, V Ramsuran - Advanced Genetics, 2023 - Wiley Online Library
Infectious diseases such as malaria, tuberculosis (TB), human immunodeficiency virus (HIV),
and the coronavirus disease of 2019 (COVID‐19) are problematic globally, with high …

Polymorphisms in the IFNγ, IL‐10, and TGFβ Genes May Be Associated with HIV‐1 Infection

F Bonfim Freitas, S Souza Lima, RNM Feitosa… - Disease …, 2015 - Wiley Online Library
Objective. This study investigated possible associations between the TNFα‐308G/A, IFN+
874A/T, IL‐6‐174C/G, IL‐10‐1082A/G, and TGFβ‐509C/T polymorphisms with HIV‐1 …

Genetic polymorphisms associated with rubella virus-specific cellular immunity following MMR vaccination

RB Kennedy, IG Ovsyannikova, IH Haralambieva… - Human genetics, 2014 - Springer
Rubella virus causes a relatively benign disease in most cases, although infection during
pregnancy can result in serious birth defects. An effective vaccine has been available since …

[HTML][HTML] The Enigmatic Interplay of Interleukin-10 in the Synergy of HIV Infection Comorbid with Preeclampsia

SJ Naidoo, T Naicker - International Journal of Molecular Sciences, 2024 - mdpi.com
Cytokines coordinate the intricate choreography of the immune system, directing cellular
activities that mediate inflammation, pathogen defense, pathology and tissue repair. Within …