Even though cancer treatment has improved over the recent decades, still more specific and
effective treatment concepts are mandatory. Surgical removal is not always possible …

YTOCHALASINS and phalloidins are two groups of small, naturally occurring organic
molecules that bind to actin and alter its polymerization. They have been widely used to …

Tumour cells primarily utilize aerobic glycolysis for energy production, a phenomenon
known as the Warburg effect. Its mechanism is not well understood. The tumour suppressor …

Phagocytosis is a process in which target cells or particles are engulfed and taken up by
other cells, typically professional phagocytes; this process is crucial in many physiological …

Production of the proinflammatory cytokine interleukin 1β (IL-1β) by dendritic cells is crucial
in host defense. Here we identify a previously unknown role for dectin-1 in the activation of a …

The leading edge (∼ 1 μm) of lamellipodia in Xenopus laevis keratocytes and fibroblasts
was shown to have an extensively branched organization of actin filaments, which we term …

Many plants acquire freezing tolerance through cold acclimatization (CA), a prolonged
exposure to low but non‐freezing temperatures at the onset of winter. CA is associated with …

Aberrations in nuclear size and shape are commonly used to identify cancerous tissue.
However, it remains unclear whether the disturbed nuclear structure directly contributes to …

The chemistry and biology of cytochalasans - Natural Product Reports (RSC Publishing) DOI:10.1039/B903913A
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/B903913A …

Actions of cytochalasin B (CB) on cytoskeletons and motility of growth cones from cultured
Aplysia neurons were studied using a rapid flow perfusion chamber and digital video light …