Immunoporosis: immunology of osteoporosis—role of T cells

RK Srivastava, HY Dar, PK Mishra - Frontiers in immunology, 2018 - frontiersin.org
The role of immune system in various bone pathologies, such as osteoporosis, osteoarthritis,
and rheumatoid arthritis is now well established. This had led to the emergence of a modern …

Gut microbiota and bone metabolism

L Lu, X Chen, Y Liu, X Yu - The FASEB Journal, 2021 - Wiley Online Library
Osteoporosis is the most common metabolic skeletal disease. It is characterized by the
deterioration of the skeletal microarchitecture and bone loss, leading to ostealgia, and even …

Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice

L Sapra, HY Dar, A Bhardwaj, A Pandey, S Kumari… - Scientific reports, 2021 - nature.com
Osteoporosis is a systemic-skeletal disorder characterized by enhanced fragility of bones
leading to increased rates of fractures and morbidity in large number of populations …

Integrated bioinformatic analysis of the shared molecular mechanisms between osteoporosis and atherosclerosis

L Mo, C Ma, Z Wang, J Li, W He, W Niu… - Frontiers in …, 2022 - frontiersin.org
Background Osteoporosis and atherosclerosis are common in the elderly population,
conferring a heavy worldwide burden. Evidence links osteoporosis and atherosclerosis but …

The correlation between the Th17/Treg cell balance and bone health

L Zhu, F Hua, W Ding, K Ding, Y Zhang, C Xu - Immunity & Ageing, 2020 - Springer
With the ageing of the world population, osteoporosis has become a problem affecting
quality of life. According to the traditional view, the causes of osteoporosis mainly include …

Role of NFAT5 in the immune system and pathogenesis of autoimmune diseases

N Lee, D Kim, WU Kim - Frontiers in Immunology, 2019 - frontiersin.org
The nuclear factor of activated T cells (NFAT5), also known as a tonicity-responsive
enhancer-binding protein, was originally identified as a key transcription factor involved in …

[HTML][HTML] Remodeling of the osteoimmune microenvironment after biomaterials implantation in murine tibia: Single-cell transcriptome analysis

J Li, C Zhao, Y Xu, L Song, Y Chen, Y Xu, Y Ma… - Bioactive materials, 2023 - Elsevier
Osseointegration seems to be a foreign body reaction equilibrium due to the complicated
interactions between the immune and skeletal systems. The heterogeneity of the …

Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis …

Z Azam, L Sapra, K Baghel, N Sinha, RK Gupta, V Soni… - Cells, 2023 - mdpi.com
Osteoporosis is a systemic skeletal disease characterised by low bone mineral density
(BMD), degeneration of bone micro-architecture, and impaired bone strength. Cissus …

The modulatory effect of high salt on immune cells and related diseases

X Li, A Alu, Y Wei, X Wei, M Luo - Cell proliferation, 2022 - Wiley Online Library
Background The adverse effect of excessive salt intake has been recognized in decades.
Researchers have mainly focused on the association between salt intake and hypertension …

A review of the world's salt reduction policies and strategies–preparing for the upcoming year 2025

T Nie, S Huang, Y Yang, A Hu, J Wang, Z Cheng… - Food & Function, 2024 - pubs.rsc.org
Excessive consumption of dietary sodium is a significant contributor to non-communicable
diseases, including hypertension and cardiovascular disease. There is now a global …