Pharmacological activities and molecular mechanisms of Pulsatilla saponins

J Zhong, L Tan, M Chen, C He - Chinese Medicine, 2022 - Springer
Saponins are found in a variety of higher plants and display a wide range of
pharmacological activities, including expectorant, anti-inflammatory, vasoprotective and …

Saponins as cytotoxic agents: An update (2010–2021). Part II—Triterpene saponins

I Podolak, K Grabowska, D Sobolewska… - Phytochemistry …, 2023 - Springer
Saponins make up an important group of natural glycosidic compounds which are
distinguished by triterpene or steroidal aglycone. Although widely distributed in terrestrial …

[HTML][HTML] Chinese medicine formula 'Baipuhuang Keli'inhibits triple-negative breast cancer by hindering DNA damage repair via MAPK/ERK pathway

S Mi, X Liu, L Zhang, Y Wang, L Sun, S Yuan… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Baipuhuang Keli (BPH, constituted by Bai Tou
Weng (Pulsatilla chinensis (Bunge) Regel), Pu Gong Ying (Taraxacum mongolicum Hand …

[HTML][HTML] Pulsatilla chinensis: A review of traditional uses, phytochemistry and pharmacology research progress

Z Zhao, M Nian, H Qiao, B Li, X Zheng - Arabian Journal of Chemistry, 2021 - Elsevier
This paper is intended to review advances in the botanical, traditional uses, phytochemical
and pharmacological studies of the Pulsatilla chinensis. Up to date, 68 kinds of chemical …

The derivatives of Pulsatilla saponin A, a bioactive compound from Pulsatilla chinensis: Their synthesis, cytotoxicity, haemolytic toxicity and mechanism of action

X Tong, L Han, H Duan, Y Cui, Y Feng, Y Zhu… - European Journal of …, 2017 - Elsevier
The strong haemolytic toxicity of Pulsatilla saponin A (PSA) has hampered its clinical
development as an injectable anticancer agent. To circumvent this challenge, twenty PSA …

Pulsatilla saponin A induces apoptosis and differentiation of myeloma cells

B Ye, Y Zhou, Y Liu, X Li, T Li… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Objectives: To investigate the performance of Pulsatilla saponin A (PsA) in Multiple Myeloma
(MM) cells. Methods: Proliferation, cell cycle analysis, apoptosis and TUNEL assays were …

[PDF][PDF] 白头翁皂苷PSA 对SW480 人结直肠癌细胞糖酵解途径关键蛋白及调节因子HIF⁃ 1α 的影响

崔亚茹, 王慧玲, 陈兰英, 官紫祎… - injury [J], 2018 - pmt5b327c-pic7.websiteonline.cn
目的探讨白头翁皂苷PSA 对人结直肠癌SW480 细胞糖酵解的影响. 方法MTT
法检测细胞存活率; 分光光度试剂盒检测葡萄糖消耗及糖酵解产物; 荧光定量PCR …

Advances in anti-tumor effects and mechanisms of Pulsatilla Chinensis saponins and its monomers.

H Song, Z Xiang, S Xue, Q Miao… - Journal of Chinese …, 2021 - search.ebscohost.com
As a traditional Chinese herbal medicine, Pulsatilla Chinensis (P. Chinensis) is widely used
in the clinical practice of traditional Chinese medicine (TCM). Recently, medical research …

Application of linear gradient elution in countercurrent chromatography for the separation of triterpenoid saponins from the roots of Pulsatilla koreana Nakai

KJ Lee, K Song, DY Song… - Journal of separation …, 2017 - Wiley Online Library
A linear gradient elution method using countercurrent chromatography was developed for
the separation of four triterpenoid saponins from the roots of Pulsatilla koreana Nakai …

[PDF][PDF] Saponins as cytotoxic agents: an update (2010–2021). Part II—Triterpene saponins

IPKGD Sobolewska, DWBJ Makowska-Was, A Galanty - portalwiedzy.cm-uj.krakow.pl
Saponins make up an important group of natural glycosidic compounds which are
distinguished by triterpene or steroidal aglycone. Although widely distributed in terrestrial …