[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

Drinking problems: mechanisms of macropinosome formation and maturation

CM Buckley, JS King - The FEBS journal, 2017 - Wiley Online Library
Macropinocytosis is a mechanism for the nonspecific bulk uptake and internalisation of
extracellular fluid. This plays specific and distinct roles in diverse cell types such as …

[HTML][HTML] The influence of dysfunctional signaling and lipid homeostasis in mediating the inflammatory responses during atherosclerosis

ML Buckley, DP Ramji - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Atherosclerosis, the underlying cause of myocardial infarction and thrombotic
cerebrovascular events, is responsible for the majority of deaths in westernized societies …

The potential of probiotics in the prevention and treatment of atherosclerosis

VL O'Morain, DP Ramji - Molecular nutrition & food research, 2020 - Wiley Online Library
Atherosclerosis, the underlying cause of cardiovascular diseases such as myocardial
infarction, cerebrovascular accident, and peripheral vascular disease, is the leading cause …

Novel insights: Dynamic foam cells derived from the macrophage in atherosclerosis

J Li, Q Meng, Y Fu, X Yu, T Ji, Y Chao… - Journal of cellular …, 2021 - Wiley Online Library
Atherosclerosis can be regarded as a chronic disease derived from the interaction between
disordered lipoproteins and an unsuitable immune response. The evolution of foam cells is …

Interferons as essential modulators of atherosclerosis

MCS Boshuizen, MPJ de Winther - … , thrombosis, and vascular …, 2015 - Am Heart Assoc
Interferons (IFNs) are key regulators of both innate and adaptive immune responses. The
family of IFN cytokines can be divided into 3 main subtypes of which type I and type II IFNs …

High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types

L Blanc, IB Daudelin, BK Podell, PY Chen… - Elife, 2018 - elifesciences.org
Understanding the distribution patterns of antibiotics at the site of infection is paramount to
selecting adequate drug regimens and developing new antibiotics. Tuberculosis (TB) lung …

Cell-penetrating peptides delivering siRNAs: an overview

L Falato, M Gestin, Ü Langel - Design and Delivery of SiRNA Therapeutics, 2021 - Springer
Abstract Cell-Penetrating Peptides (CPP) are valuable tools capable of crossing the plasma
membrane to deliver therapeutic cargo inside cells. Small interfering RNAs (siRNA) are …

The pervasiveness of macropinocytosis in oncological malignancies

C Commisso - … Transactions of the Royal Society B, 2019 - royalsocietypublishing.org
In tumour cells, macropinocytosis functions as an amino acid supply route and supports
cancer cell survival and proliferation. Initially demonstrated in oncogenic KRAS-driven …

[HTML][HTML] Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis

H Gallagher, JO Williams, N Ferekidis, A Ismail… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Atherosclerosis and its complications are responsible for one in three global deaths.
Nutraceuticals show promise in the prevention and treatment of atherosclerosis but require …