Mechanistic aspects of medicinal plants and secondary metabolites against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
K Malekmohammad… - Current pharmaceutical …, 2021 - ingentaconnect.com
Background and Objective: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2), a highly pathogenic virus, is responsible for a respiratory disease termed coronavirus …
2), a highly pathogenic virus, is responsible for a respiratory disease termed coronavirus …
Screening S protein–ACE2 blockers from natural products: strategies and advances in the discovery of potential inhibitors of COVID-19
H Liu, X Liu, X Yuan, C Xu, F Wang, J Lin, R Xu… - European Journal of …, 2021 - Elsevier
Abstract The Coronavirus disease, 2019 (COVID-19) is caused by severe acute respiratory
syndrome Coronavirus 2 (SARS-CoV-2), which poses a major threat to human life and …
syndrome Coronavirus 2 (SARS-CoV-2), which poses a major threat to human life and …
β-Caryophyllene, a natural dietary CB2 receptor selective cannabinoid can be a candidate to target the trinity of infection, immunity, and inflammation in Covid-19
NK Jha, C Sharma, HM Hashiesh… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease (COVID-19), caused by novel severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is an ongoing pandemic and presents a public health …
coronavirus 2 (SARS-CoV-2), is an ongoing pandemic and presents a public health …
Macrolactin A as a Novel Inhibitory Agent for SARS-CoV-2 Mpro: Bioinformatics Approach
COVID-19 is a disease that puts most of the world on lockdown and the search for
therapeutic drugs is still ongoing. Therefore, this study used in silico screening to identify …
therapeutic drugs is still ongoing. Therefore, this study used in silico screening to identify …
Design, synthesis, molecular docking, dynamics simulations and antiviral activities of quinoline derivatives
The designed and synthesized quinoline derivatives were screened for their anti-RSV, anti-
YFV and broad spectrum anti-viral activity. Initially, physicochemical and drug-like properties …
YFV and broad spectrum anti-viral activity. Initially, physicochemical and drug-like properties …
Mahanimbine isolated from Murraya koenigii inhibits P-glycoprotein involved in lung cancer chemoresistance
Abstract P-glycoprotein (P-gp), a transmembrane glycoprotein, is mainly involved in lung
cancer multidrug resistance. Several P-gp inhibitors have been developed to enhance the …
cancer multidrug resistance. Several P-gp inhibitors have been developed to enhance the …
Dietary bioactive diindolylmethane enhances the therapeutic efficacy of centchroman in breast cancer cells by regulating ABCB1/P-gp efflux transporter
Overexpression of drug efflux transporters is commonly associated with multidrug-resistance
in cancer therapy. Here for the first time, we investigated the ability of diindolylmethane …
in cancer therapy. Here for the first time, we investigated the ability of diindolylmethane …
Promising phytochemicals of traditional Himalayan medicinal plants against putative replication and transmission targets of SARS-CoV-2 by computational …
Background Identification and repurposing of therapeutic and preventive strategies against
COVID-19 are rapidly undergoing. Several medicinal plants from the Himalayan region have …
COVID-19 are rapidly undergoing. Several medicinal plants from the Himalayan region have …
In silico design, synthesis and anti-HIV activity of quinoline derivatives as non-nucleoside reverse transcriptase inhibitors (NNRTIs)
A series of quinoline derivatives has been designed, synthesized and screened for their anti-
HIV properties. The drug-like properties of compounds were evaluated first and then …
HIV properties. The drug-like properties of compounds were evaluated first and then …
Multifaceted roles of plant derived small molecule inhibitors on replication cycle of SARS-CoV-2
Abstract Introduction Coronavirus disease 2019 (COVID-19) is an illness caused by the new
coronavirus severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). It has …
coronavirus severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). It has …