Neurological disorders are characterized by high morbidity, disability, and mortality rates,
which seriously threaten human health. However, clinically satisfactory agents for treatment …

Brain organoids are three-dimensional (3D) structures derived from human pluripotent stem
cells (hPSCs) that reflect early brain organization. These organoids contain different cell …

Neurodegenerative diseases affect millions of people worldwide and there are currently no
cures. Two types of common neurodegenerative diseases are Alzheimer's (AD) and …

Parkinson's disease, an aging-associated neurodegenerative disorder, is characterised by
nigrostriatal pathway dysfunction caused by the gradual loss of dopaminergic neurons in the …

As an ideal in vitro model, brain‐on‐chip (BoC) is an important tool to comprehensively
elucidate brain characteristics. However, the in vitro model for the definition scope of BoC …

Understanding the signals from the physical microenvironment is critical for deciphering the
processes of neurogenesis and neurodevelopment. The discovery of how surrounding …

Parkinson's disease (PD) is a neurodegenerative disorder marked by the loss of
dopaminergic neurons in the substantia nigra. Despite progress, the pathogenesis remains …

As human life expectancy continues to increase and the birth rate continues to decline, the
phenomenon of aging is becoming more prominent worldwide. Therefore, addressing the …

Neuronal injury, aging, and cerebrovascular and neurodegenerative diseases such as
cerebral infarction, Alzheimer's disease, Parkinson's disease, frontotemporal dementia …

Neural stem cells (NSCs) are multipotent stem cells with remarkable self‐renewal potential
and also unique competencies to differentiate into neurons, astrocytes, and …