Allogeneic lung transplantation (LuTx) is considered the treatment of choice for a broad
range of advanced, progressive lung diseases resistant to conventional treatment regimens …

Allograft failure remains a major barrier in the field of lung transplantation and results
primarily from acute and chronic rejection. To date, standard-of-care immunosuppressive …

This meeting report from the XV Banff conference describes the creation of a multiorgan
transplant gene panel by the Banff Molecular Diagnostics Working Group (MDWG). This …

By definition no model is perfect, and this also holds for biology and health sciences. In
medicine, murine models are, and will be indispensable for long, thanks to their reasonable …

Background The clinical application of normothermic ex vivo lung perfusion (EVLP) has
increased donor lung utilization for transplantation through functional assessment. To …

Background Lung transplantation (LTx) is associated with sterile inflammation, possibly
related to the release of damage associated molecular patterns (DAMPs) by injured allograft …

Background. Normothermic ex vivo lung perfusion (EVLP) increases the pool of donor lungs
by requalifying marginal lungs refused for transplantation through the recovery of …

Novel tools are needed to improve diagnostic accuracy and risk prediction in BK virus
nephropathy (BKVN). We assessed the utility of intragraft gene expression testing for these …

End-stage lung disease is ultimately treated with lung transplantation. However, there is a
paucity of organs with an increasing number of patients being diagnosed with end-stage …

The quality of marginal donor lungs is clinically assessed with normothermic machine
perfusion. Although subnormothermic temperature and perfluorocarbon-based oxygen …