[HTML][HTML] In-vitro evaluation of the immunomodulatory effects of Baricitinib: Implication for COVID-19 therapy

L Petrone, E Petruccioli, T Alonzi, V Vanini, G Cuzzi… - Journal of Infection, 2021 - Elsevier
Objective Baricitinib seems a promising therapy for COVID-19. To fully-investigate its effects,
we in-vitro evaluated the impact of baricitinib on the SARS-CoV-2-specific-response using …

[HTML][HTML] T Cell Responses during Human Immunodeficiency Virus/Mycobacterium tuberculosis Coinfection

JA Bohórquez, C Jagannath, H Xu, X Wang, G Yi - Vaccines, 2024 - mdpi.com
Coinfection with Mycobacterium tuberculosis (Mtb) and the human immunodeficiency virus
(HIV) is a significant public health concern. Individuals infected with Mtb who acquire HIV …

Knockdown of circ-FANCA alleviates LPS-induced HK2 cell injury via targeting miR-93-5p/OXSR1 axis in septic acute kidney injury

H Li, X Zhang, P Wang, X Zhou, H Liang… - Diabetology & metabolic …, 2021 - Springer
Background Sepsis is life-threatening disease with systemic inflammation and can lead to
various diseases, including septic acute kidney injury (AKI). Recently, diverse circular RNAs …

HIV infection functionally impairs Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses

P Amelio, D Portevin, J Hella, K Reither… - Journal of …, 2019 - Am Soc Microbiol
Human immunodeficiency virus (HIV) infection is the major risk factor predisposing for
Mycobacterium tuberculosis progression from latent tuberculosis infection (LTBI) to …

Effect of HIV-infection on QuantiFERON-plus accuracy in patients with active tuberculosis and latent infection

E Petruccioli, T Chiacchio, A Navarra, V Vanini… - Journal of Infection, 2020 - Elsevier
Objective HIV-infection increases the risk to progress to active-tuberculosis (TB). Detection
of latent TB infection (LTBI) is needed to eventually propose preventive-therapy and reduce …

Bayesian parametric modeling of time to tuberculosis co-infection of HIV/AIDS patients at Jimma Medical Center, Ethiopia

AK Umeta, SF Yermosa, AG Dufera - Scientific Reports, 2022 - nature.com
Tuberculosis is the most common opportunistic infection among HIV/AIDS patients, including
those following Antiretroviral Therapy treatment. The risk of tuberculosis infection is higher in …

Immunomodulatory Effects of Phosphorylated Radix Cyathulae officinalis Polysaccharides in Immunosuppressed Mice

H Feng, J Fan, L Lin, Y Liu, D Chai, J Yang - Molecules, 2019 - mdpi.com
This research aimed to investigate the immunomodulatory effects of phosphorylated Radix
Cyathulae officinalis Kuan polysaccharides (pRCPS) in immunosuppressed mice, improving …

Effect of therapy on Quantiferon-Plus response in patients with active and latent tuberculosis infection

E Petruccioli, T Chiacchio, V Vanini, G Cuzzi… - Scientific Reports, 2018 - nature.com
Lack of biomarkers for treatment monitoring is listed among the main requirements for next
generation assays, as identified globally among tuberculosis (TB) researchers. In this study …

Evaluation of the immunomodulatory effects of interleukin-10 on peripheral blood immune cells of COVID-19 patients: Implication for COVID-19 therapy

S Najafi-Fard, E Petruccioli, C Farroni… - Frontiers in …, 2022 - frontiersin.org
Objective Several therapies with immune-modulatory functions have been proposed to
reduce the overwhelmed inflammation associated with COVID-19. Here we investigated the …

VIDAS® TB-IGRA reagents induce a CD4+ and CD8+ T-cell IFN-γ response for both TB infection and active TB

E Petruccioli, C Farroni, G Cuzzi… - … of Tuberculosis and …, 2022 - ingentaconnect.com
Dear Editor, TB is one of the leading causes of death and the WHO has estimated an
additional 9.9 million new TB cases in 2020. 1 Global control and elimination of TB can be …