PSnpBind: a database of mutated binding site protein–ligand complexes constructed using a multithreaded virtual screening workflow
A key concept in drug design is how natural variants, especially the ones occurring in the
binding site of drug targets, affect the inter-individual drug response and efficacy by altering …
binding site of drug targets, affect the inter-individual drug response and efficacy by altering …
PSnpBind-ML: predicting the effect of binding site mutations on protein-ligand binding affinity
Protein mutations, especially those which occur in the binding site, play an important role in
inter-individual drug response and may alter binding affinity and thus impact the drug's …
inter-individual drug response and may alter binding affinity and thus impact the drug's …