[HTML][HTML] CD20+ T cells: an emerging T cell subset in human pathology

AYS Lee - Inflammation Research, 2022 - Springer
Introduction Although CD20 is classically a B cell marker, in the last three decades, dim
expression has been noted on a subset of T cells as well that has been independently …

Common variable immunodeficiency: diagnosis, management, and treatment

JK Abbott, EW Gelfand - Immunology and Allergy …, 2015 - immunology.theclinics.com
Common variable immunodeficiency (CVID) refers to a grouping of antibody deficiencies
that lack a more specific genetic or phenotypic classification. It is the immunodeficiency …

[HTML][HTML] Pathogenesis of autoimmunity in common variable immunodeficiency

K Warnatz, RE Voll - Frontiers in immunology, 2012 - frontiersin.org
Common variable immunodeficiency (CVID) presents in up to 25% of patients with
autoimmune (AI) manifestations. Given the frequency and early onset in some patients with …

CD22 ligation inhibits downstream B cell receptor signaling and Ca2+ flux upon activation

N Sieger, SJ Fleischer, HE Mei, K Reiter… - Arthritis & …, 2013 - Wiley Online Library
Objective CD22 is a surface molecule exclusively expressed on B cells that regulates
adhesion and B cell receptor (BCR) signaling as an inhibitory coreceptor of the BCR …

MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment

TW Mudd Jr, C Lu, JD Klement, K Liu - Cellular immunology, 2021 - Elsevier
The majority of human colorectal cancer remains resistant to immune checkpoint inhibitor
(ICI) immunotherapy, but the underlying mechanism is incompletely understood. We report …

[HTML][HTML] Seronegative celiac disease and immunoglobulin deficiency: where to look in the submerged iceberg?

F Giorgio, M Principi, G Losurdo, D Piscitelli, A Iannone… - Nutrients, 2015 - mdpi.com
In the present narrative review, we analyzed the relationship between seronegative celiac
disease (SNCD) and immunoglobulin deficiencies. For this purpose, we conducted a …

Impaired Akt phosphorylation in B-cells of patients with common variable immunodeficiency

R Yazdani, M Ganjalikhani-Hakemi, M Esmaeili… - Clinical …, 2017 - Elsevier
Common variable immunodeficiency (CVID) is a heterogeneous group of primary
immunodeficiency characterized by recurrent infections. We evaluated whether defective …

Evaluation of known defective signaling-associated molecules in patients who primarily diagnosed as common variable immunodeficiency

R Yazdani, H Abolhassani, N Rezaei… - International reviews …, 2016 - Taylor & Francis
Common variable immunodeficiency (CVID) is a primary immunodeficiency disease,
associated with defective antibody production and recurrent infections. Several defective …

The autoimmune conundrum in common variable immunodeficiency disorders

AAJM van de Ven, K Warnatz - Current opinion in allergy and …, 2015 - journals.lww.com
The increasing comprehension of immunological concepts promoting AID in CVID will allow
better and in some cases possibly even targeted treatment. A genetic diagnosis therefore …

[HTML][HTML] PD1+ CD4+ T cells promote receptor editing and suppress autoreactivity of CD19+ CD21low B cells within the lower respiratory airways in adenovirus …

B Lu, Y Zhang, J Wang, D Yang, M Liu, L Ma, W Yi… - Mucosal …, 2024 - Elsevier
Human adenovirus (HAdV) pneumonia poses a major health burden for young children,
however, factors that contribute to disease severity remain elusive. We analyzed immune …