Inactivating mutations of the tumor suppressor gene Liver Kinase B1 (LKB1) are frequently
detected in non‐small‐cell lung cancer (NSCLC) and cervical carcinoma. Moreover, LKB1 …

TP53 is a tumor suppressor gene that encodes a sequence-specific DNA-binding
transcription factor activated by stressful stimuli; it upregulates target genes involved in …

Multiple myeloma (MM) is the second most common hematological cancer and is
characterized by genetic features including translocations, chromosomal copy number …

Lung cancer represents the world's leading cause of cancer deaths. Sex differences in the
incidence and mortality rates for various types of lung cancers have been identified, but the …

We aim to provide an overview of the research available on indoor radon and lung cancer,
with a special focus on Spanish investigations. Early studies on underground miners …

Lung cancer poses the greatest cancer-related death risk and males have poorer outcomes
than females, for unknown reasons. Patient sex is not a biological variable considered in …

Abstract Background Activator protein-1 (AP-1) represents a transcription factor family that
has garnered growing attention for its extensive involvement in tumor biology. However, the …

The TP53 gene is the most frequently mutated gene in human cancers, and the majority of
TP53 mutations are missense mutations. As a result, these mutant p53 (mutp53) either …

Lung cancer (LC) continues to pose the highest mortality and exhibits a common prevalence
among all types of cancer. The genetic interaction between human eukaryotes and microbial …

Background: Poor patients often reside in neighborhoods of lower socioeconomic status
(SES) with high levels of airborne pollutants. They also have higher mortality from non–small …