Recent studies have established that dysregulation of the human immune system and the
reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight …

The Wnt signaling pathway is critically involved in both the development and homeostasis of
tissues via regulation of their endogenous stem cells. Aberrant Wnt signaling has been …

Background Extracellular matrix (ECM) is a dynamic and complex environment
characterized by biophysical, mechanical and biochemical properties specific for each …

Abstract Characterization of how the microenvironment, or niche, regulates stem cell activity
is central to understanding stem cell biology and to developing strategies for the therapeutic …

The bone marrow niche has mystified scientists for many years, leading to widespread
investigation to shed light into its molecular and cellular composition. Considerable efforts …

Transplantation of hematopoietic stem cells (HSCs) from human umbilical cord blood
(hUCB) holds great promise for treating a broad spectrum of hematological disorders …

Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

The existence of a haematopoietic stem cell niche as a spatially confined regulatory entity
relies on the notion that haematopoietic stem and progenitor cells (HSPCs) are strategically …

The intermediate filament protein Nestin labels populations of stem/progenitor cells,
including self-renewing mesenchymal stem cells (MSCs), a major constituent of the …

Atherosclerosis: the interplay between lipids and immune cel... : Current Opinion in Lipidology
Atherosclerosis: the interplay between lipids and immune cells : Current Opinion in Lipidology …