Improved understanding and management of COVID-19, a potentially life-threatening
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …

Leishmaniases are a group of diseases caused by protozoa of the genus Leishmania that
affect millions of people worldwide. These diseases are caused by distinct Leishmania …

A protective or deleterious role of CD8+ T cells in human cutaneous leishmaniasis (CL) has
been debated. The present report explores the participation of CD8+ T cells in disease …

Aims Our aim was to investigate the skin‐homing T‐cell immune responses triggered in
patients with Demodex infestation and/or rosacea. Methods Collected whole blood samples …

Leishmania (Viannia) braziliensis induces American tegumentary leishmaniasis that ranges
in severity from the milder form, cutaneous (CL) to severe disseminated cutaneous …

Cytotoxic activity mediated by CD8+ T cells is the main signature of the
immunopathogenesis of cutaneous leishmaniasis (CL). Here, we performed a broad …

The aim of this work was to define the population of regulatory T cells (Tregs) which are
circulating in the blood of Leishmania infected individuals clinically displaying a lesion …

Immunopathological studies have contributed to the characterization of in situ inflammatory
infiltrates in cutaneous leishmaniasis (CL). However, little is known about the T-cell antigen …

Leishmania (Viannia) braziliensis control and tissue damage relate to the effector immune
response, which in turn affects clinical outcome. Leishmania reactive CD4+ and CD8+ T …

A high number of Leishmania-responder T cells is found in cutaneous leishmaniasis lesions,
suggesting that important immunological events occur at the site of infection. Although …