The regulator of G protein signaling (RGS) family of proteins serves critical roles in G protein- coupled receptor (GPCR) and heterotrimeric G protein signal transduction. RGS proteins are …
Dopamine input to the dorsal and ventral striatum originates from separate populations of midbrain neurons. Despite differences in afferent inputs and behavioral output, little is …
Signaling via heterotrimeric G proteins plays a crucial role in modulating the responses of striatal neurons that ultimately shape core behaviors mediated by the basal ganglia circuitry …
Regulators of G protein signaling control the duration and extent of signaling via G protein- coupled receptor (GPCR) pathways by accelerating the GTP hydrolysis on G protein α …
Regulator of G protein signaling (RGS) proteins play essential roles in the regulation of signaling via G protein-coupled receptors (GPCRs). With hundreds of GPCRs and dozens of …
A Fajardo‐Serrano, N Wydeven, D Young… - …, 2013 - Wiley Online Library
In the hippocampus, signaling through G protein‐coupled receptors is modulated by Regulators of G protein signaling (Rgs) proteins, which act to stimulate the rate of GTP …
F Sakloth, C Polizu, F Bertherat, V Zachariou - Molecular Pharmacology, 2020 - ASPET
Regulator of G protein signaling (RGS) proteins are multifunctional proteins expressed in peripheral and neuronal cells, playing critical roles in development, physiologic processes …
In the striatum, signaling through G protein-coupled dopamine receptors mediates motor and reward behavior, and underlies the effects of addictive drugs. The extent of receptor …
Signaling by the G-protein-coupled receptors (GPCRs) plays fundamental role in a vast number of essential physiological functions. Precise control of GPCR signaling requires …