Probiotics and related preparations, including synbiotics and postbiotics, are living and non-
living microbial-based multi-components, which are now among the most popular bioactive …

Multiple genetic alterations are associated with prostate carcinogenesis. Tumor-suppressor
genes phosphatase and tensin homolog deleted on chromosome 10 (Pten) and androgen …

Primary prostate tumor heterogeneity is poorly understood, leaving research efforts with
challenges regarding the initiation and advancement of the disease. The growth of tumor …

Cancer tissues are composed of various cell types including cancer cells, cancer-associated
fibroblasts (CAFs), tumor-associated macrophages (TAMs) and endothelial cells. These …

Background Previous studies have shown the value in studying lineage tracing in slices of
human tumors. However, a tumor is not a two-dimensional structure and to better …

La presente tesis doctoral se ha centrado en el estudio de la variabilidad del DNA
mitocondrial (DNAmt) por secuenciación masiva (NGS) y el impacto de dicha variabilidad …

Lineage tracing is a basic concept in developmental biology, as well as diseases related to
organ development. A reliable method to track cell lineages in human tissues has the …