Cardiovascular diseases are a leading cause of death worldwide. Current treatments
directed at heart repair have several disadvantages, such as a lack of donors for heart …

This review article will cover the recent developments in the new evolving field of Purkinje
bioengineering and the development of human Purkinje networks. Recent work has …

Abstract Development of tissue-engineered hearts for treatment of myocardial infarction or
biologic pacemakers has been hindered by the production of mostly arrhythmic or in …

Current cell seeding techniques focus on passively directing cells to a scaffold surface with
the addition of dynamic culture to encourage cell permeation. In 3D tissue engineered …

Clinical trials using human adipogenic mesenchymal stem cells (hAdMSCs) for the
treatment of cardiac diseases have shown improvement in cardiac function and were proven …

Current physical stimuli mechanical stretch bioreactor studies focus on conditioning planar
and/or tubular engineered cardiac constructs. The current 3D bioreactor models in cardiac …

The field of biological pumps is a subset of cardiac tissue engineering and focused on the
development of tubular grafts that are designed generate intraluminal pressure. In the …

Left ventricle and aortic valve underdevelopment are presentations in the congenital cardiac
condition hypoplastic left heart syndrome (HLHS); current clinical treatments involve right …

Pediatric heart surgery remains challenging due to the small size of the pediatric heart, the
severity of congenital abnormalities and the unique characteristics of each case. New tools …

Cardiovascular pathologies are the leading cause of morbidity and mortality worldwide.
While heart transplant remains the gold standard, it is limited by the lack of donors, the …