Therapeutic vaccines for colorectal cancer: The progress and future prospect

M Shahnazari, P Samadi, M Pourjafar… - International …, 2020 - Elsevier
Cancer vaccines are usually derived from the patient's tumor cells or the antigens found on
their surface, which may help the immune system to identify and kill these malignant cells …

[HTML][HTML] Advances in the study of antitumour immunotherapy for Newcastle disease virus

Q Meng, J He, L Zhong, Y Zhao - International journal of medical …, 2021 - ncbi.nlm.nih.gov
This article reviews the preclinical research, clinical application and development of
Newcastle disease virus (NDV) in the field of cancer therapy. Based on the distinctive …

[HTML][HTML] The combination therapy of oncolytic HSV-1 armed with anti-PD-1 antibody and IL-12 enhances anti-tumor efficacy

X Xie, J Lv, W Zhu, C Tian, J Li, J Liu, H Zhou… - Translational …, 2022 - Elsevier
Cancer immunotherapy is a new therapeutic strategy for cancer treatment that targets tumors
by improving or restoring immune system function. Therapies targeting immune checkpoint …

[HTML][HTML] Interleukin-12 Delivery Strategies and Advances in Tumor Immunotherapy

C Dong, D Tan, H Sun, Z Li, L Zhang, Y Zheng… - Current Issues in …, 2024 - mdpi.com
Interleukin-12 (IL-12) is considered to be a promising cytokine for enhancing an antitumor
immune response; however, recombinant IL-12 has shown significant toxicity and limited …

Oncolytic viruses against cancer, promising or delusion?

A Letafati, OS Ardekani, M Naderisemiromi, MM Fazeli… - Medical Oncology, 2023 - Springer
Cancer treatment is one of the most challenging topics in medical sciences. Different
methods such as chemotherapy, tumor surgery, and immune checkpoint inhibitors therapy …

[HTML][HTML] A Mini-review on Oncolytic Newcastle Disease Virus (NDV): From Highly Contagious Virus to a Biological Tool for Cancer Therapy

SUFS Najmuddin, AA Kamarudin… - The Open …, 2023 - openbiotechnologyjournal.com
Newcastle disease virus is a highly contagious viral infection affecting a plethora of avian
species with distinct levels of susceptibility. It exerts a significant economic impact in certain …

Strategies to develop potent oncolytic viruses and enhance their therapeutic efficacy

O Moaven, CW Mangieri, JA Stauffer… - JCO precision …, 2021 - ascopubs.org
Despite advancements in cancer therapy that have occurred over the past several decades,
successful treatment of advanced malignancies remains elusive. Substantial resources and …

The Application of Newcastle Disease Virus (NDV): Vaccine Vectors and Tumor Therapy

H Yang, J Tian, J Zhao, Y Zhao, G Zhang - Viruses, 2024 - mdpi.com
Newcastle disease virus (NDV) is an avian pathogen with an unsegmented negative-strand
RNA genome that belongs to the Paramyxoviridae family. While primarily pathogenic in …

The influence of a modified p53 C-terminal peptide by using a tumor-targeting sequence on cellular apoptosis and tumor treatment

X Guo, Y Zhang, Q Li, F Shi, Y HuangFu, J Li, X Lao - Apoptosis, 2024 - Springer
The restoration of the function of p53 in tumors is a therapeutic strategy for the highly
frequent mutation of the TP53 tumor suppressor gene. P460 is a wild-type peptide derived …

Autophagy inhibition suppresses Newcastle disease virus-induced cell death by inhibiting viral replication in human breast cancer cells

MI Rozilah, K Yusoff, SL Chia, S Ismail - Virology, 2024 - Elsevier
Newcastle disease virus (NDV) is an oncolytic virus which selectively replicates in cancer
cells without harming normal cells. Autophagy is a cellular mechanism that breaks down …