Cancer, infectious diseases, and metabolic and hereditary genetic disorders are a global
health burden affecting millions of people, with contemporary treatments offering limited …

Radiotherapy and chemotherapy are two famous modalities in tumor‐targeted therapy that
lead to systemic and local toxicities for normal tissues. Moreover, several studies have …

Porphyromonas gingivalis is a gram-negative anaerobic periodontal pathogen that persists
in dysbiotic mixed-species biofilms alongside a dense inflammatory infiltrate of neutrophils …

Antisense oligonucleotides (ASOs) are a novel therapeutic approach to target difficult-to-
drug protein classes by targeting their corresponding mRNAs. Significantly enhanced ASO …

Hidradenitis suppurativa/acne inversa (HS) is a chronic inflammatory disease involving hair
follicles that presents with painful nodules, abscesses, fistulae, and hypertrophic scars …

Traumatic brain injury (TBI) is one of the leading causes of death worldwide. Long non-
coding RNAs (LncRNAs) have been reported to be closely associated with various …

Although the pathogenesis of primary myelofibrosis (PMF) and other myeloproliferative
neoplasms (MPNs) is linked to constitutive activation of the JAK-STAT pathway, JAK …

Hidradenitis suppurativa (HS) is a recurrent inflammatory skin disease with a complex
etiopathogenesis whose treatment poses a challenge in the clinical practice. Here, we …

The two main reasons for death of cancer patients, tumor recurrence and metastasis, are
multi-stage cellular processes that involve increased cell plasticity and coincide with …

In this study, we investigated the functional role of isoprenylcysteine carboxyl
methyltransferase (ICMT) and its methylatable substrate Ras in Toll-like receptor (TLR) …