Alzheimer's disease (AD) is a neurodegenerative disease that is of high importance to the
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …

Astrocytes are glial cells that are distributed throughout the central nervous system in an
arrangement optimal for chemical and physical interaction with neuronal synapses and …

Luteolin is a flavonoid in a variety of fruits, vegetables, and herbs, which has shown anti-
inflammatory, antioxidant, and anti-cancer neuroprotective activities. In this study, we …

Background Neuroinflammation plays an important role in the onset and progression of
neurodegenerative diseases such as Alzheimer's disease. Lipopolysaccharide (LPS …

Background The FDA-approved small-molecule drug dasatinib is currently used as a
treatment for chronic myeloid leukemia (CML). However, the effects of dasatinib on …

Human pancreatic islet amyloid polypeptide (hIAPP) and beta amyloid (Aβ) can accumulate
in Type 2 diabetes (T2D) and Alzheimer's disease (AD) brains and evidence suggests that …

Amyloid beta (Aβ) is an intricate molecule that interacts with several biomolecules and/or
produces insoluble assemblies and eventually the nonphysiological depositions of its …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive
decline, the neuropathological formation of amyloid-beta (Aβ) plaques and neurofibrillary …

To date, approximately 50 proteins have been identified that can misfold and aggregate to
form amyloid fibrils and cause neurodegenerative diseases such as Alzheimer disease …

Apolipoprotein E4 (ApoE4) is the main genetic risk factor for Alzheimer's disease (AD), but
the exact way in which it causes AD remains unclear. Curcumin is considered to have good …