Canonical and ECF-type ATP-binding cassette importers in prokaryotes: diversity in modular organization and cellular functions

T Eitinger, DA Rodionov, M Grote… - FEMS microbiology …, 2011 - academic.oup.com
Since their discovery in the 1960s as 'osmotic shock-sensitive'transporters, a plethora of so-
called binding protein-dependent (canonical) ATP-binding cassette (ABC) importers has …

The Key Element Role of Metallophores in the Pathogenicity and Virulence of Staphylococcus aureus: A Review

G Ghssein, Z Ezzeddine - Biology, 2022 - mdpi.com
Simple Summary Metallophores, which are secondary metabolites secreted by bacteria,
play an important role in their virulence. The bacterium Staphylococcus aureus produces …

Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus

G Ghssein, C Brutesco, L Ouerdane, C Fojcik, A Izaute… - Science, 2016 - science.org
Metal acquisition is a vital microbial process in metal-scarce environments, such as inside a
host. Using metabolomic exploration, targeted mutagenesis, and biochemical analysis, we …

Amino Acid Catabolism in Staphylococcus aureus and the Function of Carbon Catabolite Repression

CR Halsey, S Lei, JK Wax, MK Lehman, AS Nuxoll… - MBio, 2017 - Am Soc Microbiol
Staphylococcus aureus must rapidly adapt to a variety of carbon and nitrogen sources
during invasion of a host. Within a staphylococcal abscess, preferred carbon sources such …

Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence‐determinant stability

SL Kolar, J Antonio Ibarra, FE Rivera… - …, 2013 - Wiley Online Library
Staphylococcus aureus is a highly virulent and successful pathogen that causes a diverse
array of diseases. Recently, an increase of severe infections in healthy subjects has been …

Two Novel Point Mutations in Clinical Staphylococcus aureus Reduce Linezolid Susceptibility and Switch on the Stringent Response to Promote Persistent Infection

W Gao, K Chua, JK Davies, HJ Newton… - PLoS …, 2010 - journals.plos.org
Staphylococcus aureus frequently invades the human bloodstream, leading to life
threatening bacteremia and often secondary foci of infection. Failure of antibiotic therapy to …

A search for small noncoding RNAs in Staphylococcus aureus reveals a conserved sequence motif for regulation

T Geissmann, C Chevalier, MJ Cros… - Nucleic acids …, 2009 - academic.oup.com
Bioinformatic analysis of the intergenic regions of Staphylococcus aureus predicted multiple
regulatory regions. From this analysis, we characterized 11 novel noncoding RNAs (RsaA …

Defining the Environmental Adaptations of Genus Devosia: Insights into its Expansive Short Peptide Transport System and Positively Selected Genes

C Talwar, S Nagar, R Kumar, J Scaria, R Lal… - Scientific reports, 2020 - nature.com
Devosia are well known for their dominance in soil habitats contaminated with various toxins
and are best characterized for their bioremediation potential. In this study, we compared the …

Copper Stress Induces a Global Stress Response in Staphylococcus aureus and Represses sae and agr Expression and Biofilm Formation

J Baker, S Sitthisak, M Sengupta… - Applied and …, 2010 - Am Soc Microbiol
Copper is an important cofactor for many enzymes; however, high levels of copper are toxic.
Therefore, bacteria must ensure there is sufficient copper for use as a cofactor but, more …

Bacterial single-cell RNA sequencing captures biofilm transcriptional heterogeneity and differential responses to immune pressure

LE Korshoj, T Kielian - Nature Communications, 2024 - nature.com
Biofilm formation is an important mechanism of survival and persistence for many bacterial
pathogens. These multicellular communities contain subpopulations of cells that display …