In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …

Cerebrospinal fluid (CSF) is a clear, transparent fluid derived from blood plasma that
protects the brain and spinal cord against mechanical shock, provides buoyancy, clears …

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Early diagnosis of neurodegenerative disorders such as Alzheimer's (AD) or Parkinson's
disease (PD) is needed to slow down or halt the disease at the earliest stage. Cerebrospinal …

In most patients with multiple sclerosis, the disease initiates with a first attack or clinically
isolated syndrome. At this phase, magnetic resonance imaging is an important predictor of …

Background. Patients afflicted with Alzheimer′ s disease (AD) exhibit a decrease in the
cerebrospinal fluid (CSF) concentration of the 42 amino acid form of β‐amyloid (Aβ42) …

The introduction of lumbar puncture into clinical medicine over 100 years ago marks the
beginning of the study of central nervous system diseases using the human cerebrospinal …

Objective To find a panel of proteins in antemortem cerebrospinal fluid (CSF) that could be
used to differentiate between samples from Alzheimer's disease (AD) patients and samples …

There is an urgent need for novel biomarkers that can be used to improve the diagnosis,
predict the disease progression, improve our understanding of the pathology or serve as …

Analysis of the cerebrospinal fluid (CSF) proteome has proven valuable to the study of
neurodegenerative disorders. To identify new protein/pathway alterations and candidate …