Peramivir: a novel intravenous neuraminidase inhibitor for treatment of acute influenza infections

MM Alame, E Massaad, H Zaraket - Frontiers in microbiology, 2016 - frontiersin.org
Peramivir is a novel cyclopentane neuraminidase inhibitor of influenza virus. It was
approved by the Food and Drug Administration in December 2014 for treatment of acute …

Influenza therapeutics in clinical practice—challenges and recent advances

JH Beigel, FG Hayden - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
In the last few years, several new direct-acting influenza antivirals have been licensed, and
others have advanced in clinical development. The increasing diversity of antiviral classes …

Synthesis and anti-influenza virus activity of 4-oxo-or thioxo-4, 5-dihydrofuro [3, 4-c] pyridin-3 (1H)-ones

YJ Jang, R Achary, HW Lee, HJ Lee, CK Lee, SB Han… - Antiviral research, 2014 - Elsevier
A target-free approach was applied to discover anti-influenza viral compounds, where
influenza infected Madin–Darby canine kidney cells were treated 7500 different small …

The impact of early neuraminidase inhibitor therapy on clinical outcomes in patients hospitalised with influenza A-related pneumonia: a multicenter, retrospective …

L Chen, X Han, YL Li, C Zhang, X Xing - BMC Infectious Diseases, 2020 - Springer
Background Guidelines emphasize prompt antiviral treatment in severe influenza patients.
Although nearly a 50% of severe influenza present with pneumonia, the effect of early (≤ 2 …

[HTML][HTML] Protective mechanical ventilation in suspected influenza infection

LBM Pimenta, NZ Sanson, MS Volpe… - Revista da Sociedade …, 2020 - SciELO Brasil
INTRODUCTION: Patients with acute respiratory failure due to influenza require ventilatory
support. However, mechanical ventilation itself can exacerbate lung damage and increase …

[PDF][PDF] Mobile Viren bereiten Sorgen

WWHO arbeitet an Gegenstrategien - Pneumologie, 2016 - rosenfluh.ch
Sorgen bereiten der WHO gegenwärtig vor allem zwei neue Viren: Influenza A H7N9 und
MERS-CoV. Das Vogelgrippevirus H7N9 ist einer von mehreren Influenzavirusstämmen, die …

Use of neuraminidase inhibitors for prophylaxis and treatment of pandemic influenza: summary of a Faculty of Public Health meeting

S Haroon, J Middleton, EMG Milne - Journal of Public Health, 2016 - academic.oup.com
On 15th December 2014, a meeting was held at the Faculty of Public Health (FPH) to gain
views and where possible consensus on the prophylactic use among the general population …