Bacterial biofilms are highly recalcitrant to antibiotic therapies due to multiple tolerance
mechanisms. The involvement of Pseudomonas aeruginosa in a wide range of biofilm …

Abstract Mupirocin (MUP), bactroban, or pseudomonic acid is a natural crotonic acid
derivative drug extracted from Pseudomonas fluorescens which is produced by modular …

Severe cutaneous injuries may not heal spontaneously and may necessitate the use of
supplementary therapeutic methods. Electrospun nanofibers possess high porosity and …

Mupirocin (MUP) is a topical antibacterial agent used to treat superficial skin infections but
has limited application due to in vivo inactivation and plasma protein binding. A …

Spray film-forming systems (SFFSs) provide great potential for the treatment of various types
of wounds. Such systems afford to prolong the action of active substances, to prevent cross …

Skin and soft tissue infections (SSTIs) have increased problematically in hospital and
ambulatory settings due to the poor immunity of hosts and multidrug-resistant pathogens …

Mupirocin (MUP) is an effective topical antibiotic with poor skin permeability; however, its
skin permeability can be improved by a nanoemulsion formulation based on eucalyptus oil …

Multidrug resistance (MDR) has significantly increased in the past decades and the use of
nanotechnology has opened new venues for novel treatments. Nanosulfur is a potent …

Coagulase-negative staphylococci (CoNS) widely colonize the human skin and play an
active role in host defense. However, these bacteria may cause malodours and increase …

In modern medicine, one major advancement recorded is the discovery of antibiotics. For the
past decades now, the use and misuse of antibiotics have led most clinically important …