Current developments in gastric cancer: from molecular profiling to treatment strategy

M Alsina, V Arrazubi, M Diez, J Tabernero - … Reviews Gastroenterology & …, 2023 - nature.com
Gastric cancer and gastro-oesophageal junction cancer represent a global health-care
challenge. Despite the efficacy of improved chemotherapy and surgical options, these …

The Gum–Gut axis: periodontitis and the risk of gastrointestinal cancers

G Baima, DG Ribaldone, F Romano, M Aimetti… - Cancers, 2023 - mdpi.com
Simple Summary Periodontitis, a chronic inflammatory disease of the gums, and the oral
microbiome have been recently implicated in the development of various cancers. Due to …

Gut dysbiosis induces the development of mastitis through a reduction in host anti-inflammatory enzyme activity by endotoxemia

C Zhao, X Hu, L Bao, K Wu, Y Zhao, K Xiang, S Li… - Microbiome, 2022 - Springer
Background Mounting experimental evidence has shown that the gut microbiota plays a
significant role in the pathogenesis of mastitis, and clinical investigations have found that the …

Gastric microbiota dysbiosis and Helicobacter pylori infection

L Zhang, M Zhao, X Fu - Frontiers in Microbiology, 2023 - frontiersin.org
Helicobacter pylori (H. pylori) infection is one of the most common causes of gastric disease.
The persistent increase in antibiotic resistance worldwide has made H. pylori eradication …

Role of the microbiome in oral cancer occurrence, progression and therapy

Z Li, Y Liu, L Zhang - Microbial Pathogenesis, 2022 - Elsevier
The oral cavity, like other digestive or mucosal sites, contains a site-specific microbiome that
plays a significant role in maintaining health and homeostasis. Strictly speaking, the …

A literature review on the potential clinical implications of streptococci in gastric cancer

M Zi, Y Zhang, C Hu, S Zhang, J Chen, L Yuan… - Frontiers in …, 2022 - frontiersin.org
Streptococcus is widely found in nature and the human body, and most species are not
pathogenic. In recent years, studies have found that Streptococcus is associated with gastric …

Inflammatory microenvironment in gastric premalignant lesions: implication and application

S Zhang, Y Shen, H Liu, D Zhu, J Fang, H Pan… - Frontiers in …, 2023 - frontiersin.org
Gastric precancerous lesions (GPL) are a major health concern worldwide due to their
potential to progress to gastric cancer (GC). Understanding the mechanism underlying the …

Regulatory effects of oral microbe on intestinal microbiota and the illness

Y Lu, Z Li, X Peng - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Over the past decade, the association between oral health, intestinal microbiota, and
systemic diseases has been further validated. Some oral microbial species have been …

Multi-faceted attributes of salivary cell-free DNA as liquid biopsy biomarkers for gastric cancer detection

N Swarup, J Cheng, I Choi, YJ Heo, M Kordi, M Aziz… - Biomarker …, 2023 - Springer
Background Recent advances in circulating cell-free DNA (cfDNA) analysis from biofluids
have opened new avenues for liquid biopsy (LB). However, current cfDNA LB assays are …

Bidirectional mediation effects between intratumoral microbiome and host DNA methylation changes contribute to stomach adenocarcinoma

K Yue, D Sheng, X Xue, L Zhao, G Zhao… - Microbiology …, 2023 - Am Soc Microbiol
The induction of aberrant DNA methylation is the major pathway by which Helicobacter
pylori infection induces stomach adenocarcinoma (STAD). The involvement of the non-H …